2-Methyl-1-[4-(trifluoromethyl)benzoyl]piperazine CAS 1240577-75-6
| CAS No. | 1240577-75-6 |
| Molecular Formula | C13H15F3N2O |
| Molecular Weight | 272.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Methyl-1-[4-(trifluoromethyl)benzoyl]piperazine (CAS 1240577-75-6), molecular formula C13H15F3N2O and molecular weight 272.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Methyl-1-[4-(trifluoromethyl)benzoyl]piperazine (C13H15F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Methyl-1-[4-(trifluoromethyl)benzoyl]piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15F3N2O |
| Molecular Weight | 272.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 1-[4-(Trifluoromethyl)benzoyl]-1,4-diazepane (CAS 1016512-40-5)
- 1-[3-(Trifluoromethyl)benzoyl]-1,4-diazepane (CAS 1016515-38-0)
- 3-Methyl-1-[3-(trifluoromethyl)benzoyl]piperazine (CAS 1240564-79-7)
- 2-Methyl-1-[2-(trifluoromethyl)benzoyl]piperazine (CAS 1240565-74-5)
- 3-Methyl-1-[4-(trifluoromethyl)benzoyl]piperazine (CAS 1240568-20-0)
- 3-Methyl-1-[2-(trifluoromethyl)benzoyl]piperazine (CAS 1240571-05-4)
- 2-Methyl-1-[3-(trifluoromethyl)benzoyl]piperazine (CAS 1240575-10-3)
- (R)-3-(Trifluoromethyl)-5,6,7,7a,8,9,10,11-octahydropyrazino[1,2-d]pyrido[3,2-b][1,4]diazepine (CAS 2817669-26-2)
Recommended Standards
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- N-(3,4-Dihydro-2H-1-benzopyran-4-yl)-2-fluoropyridine-4-carboxamide (CAS 1304937-19-6)
- 2-Amino-N-cyclopropyl-N-(3-(trifluoromethyl)benzyl)acetamide (CAS 1353963-78-6)
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- 8-Bromo-2,3-dimethoxy-1,5-naphthyridine (CAS 2185844-02-2)
- Tert-butyl 6-hydroxy-1,2,4,5-tetrahydro-3H-benzo[d]azepine-3-carboxylate (CAS 873446-59-4)
- Benzyl 5-Methoxy-2-methylindole-3-acetate (CAS 3285-40-3)
- Tert-butyl 3,3-difluoro-4-methylene-2-oxopyrrolidine-1-carboxylate (CAS 1055306-64-3)
- 2-Fluoro-6-pyrrolidinopyridine-3-boronic acid (CAS 2132382-87-5)
- (4-benzyl-1,4-oxazepan-2-yl)methyl methanesulfonate (CAS 2904565-20-2)
- 3-Amino-4-methyl-N-(2,2,2-trifluoroethyl)benzamide (CAS 1017019-26-9)
- 2-(2,4-dichlorophenoxy)-3-nitropyridine (CAS 129199-44-6)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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