Semaglutide impurity 50 CAS 2773558-66-8
| CAS No. | 2773558-66-8 |
| Molecular Formula | C24H46N4O13 |
| Molecular Weight | 598.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Semaglutide impurity 50 (CAS 2773558-66-8), a pharmacopoeial impurity reference standard (molecular formula C24H46N4O13, MW 598.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Semaglutide impurity 50 (C24H46N4O13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Semaglutide impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H46N4O13 |
| Molecular Weight | 598.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 4 |
Related Semaglutide Standards
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
- Semaglutide Impurity 183 (CAS 159541-28-3)
Recommended Standards
- Fmoc-NMe-PEG4-NHS ester (CAS 2228857-30-3)
- (2R,2'R,3R,3'R)-4,4'-bis(benzyloxy)-3,3'-di-tert-butyl2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole (CAS 1994323-92-0)
- 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione (CAS 644962-77-6)
- (2S,2'S,3S,3'S)-4,4'-bis(benzyloxy)-3,3'-di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole (CAS 2169292-05-9)
- Metaraminol Impurity 32 (CAS CATO-C4X-225232)
- Dequalinium impurity 35 (CAS CATO-C4X-193635)
- Captopril EP Impurity B (CAS 80629-35-2)
- Hydroxychloroquine RC 2 (CAS 860715-45-3)
- 2-Amino-N-(cyanomethyl)benzamide (CAS 234444-48-5)
- Benzyl ((3-aminotetrahydrofuran-3-yl)methyl)carbamate (CAS 1158760-33-8)
- Racecadotril EP Impurity C (CAS 124735-06-4)
- Methyl 6-bromo-5-nitropicolinate (CAS 1805557-84-9)
- trans-4-(Difluoromethoxy)cyclohexanamine (CAS 1403864-40-3)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
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