(S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine CAS 1241679-75-3
| CAS No. | 1241679-75-3 |
| Molecular Formula | C10H10ClF2N |
| Molecular Weight | 217.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine.
CATO supplies (S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241679-75-3), a certified reference material (molecular formula C10H10ClF2N, MW 217.64 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, (S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClF2N |
| Molecular Weight | 217.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- (S)-2-(4-chloro-3,5-difluorophenyl)pyrrolidine (CAS 1212832-34-2)
- (R)-2-(4-chloro-3,5-difluorophenyl)pyrrolidine (CAS 1213068-61-1)
- (R)-(4-Chloro-3,5-difluorophenyl)(cyclopropyl)methanamine (CAS 1213170-92-3)
- (R)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241679-60-6)
- (R)-2-(3-chloro-2,4-difluorophenyl)pyrrolidine (CAS 1241679-62-8)
- (S)-2-(3-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1241680-70-5)
- (S)-2-(3-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241681-59-3)
- (S)-2-(2-chloro-3,6-difluorophenyl)pyrrolidine (CAS 1241682-70-1)
Recommended Standards
- (S)-2-(4-chloro-2,5-difluorophenyl)pyrrolidine (CAS 1269780-39-3)
- (S)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1270069-76-5)
- 7-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-Dioxide (CAS 89999-91-7)
- (R)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1270093-56-5)
- 1-Methylpiperidin-3-yl acetate (CAS 6659-33-2)
- 5-methyl-4-(3-methylcyclohexyl)-4H-1,2,4-triazole-3-thiol (CAS 1096306-89-6)
- 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-(trifluoromethyl)pyridine (CAS 477711-20-9)
- Ethyl 2,6-dibromo-4-(difluoromethoxy)phenylacetate (CAS 1803774-82-4)
- 1-(5-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1156854-36-2)
- 2-(5-(3-Methoxyphenyl)isoxazol-3-yl)acetonitrile (CAS 1207022-32-9)
- 2-Chloro-N-(2-((3-cyano-6-methylquinolin-2-yl)amino)ethyl)benzamide (CAS 606105-48-0)
- 1-(Cyclopropylsulfonyl)-N-(3-(methylsulfonamido)phenyl)azetidine-3-carboxamide (CAS 1428363-32-9)
- 1,1'-Disulfanediylbis(azepan-2-one) (CAS 23847-08-7)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
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