(S)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine CAS 1270069-76-5
| CAS No. | 1270069-76-5 |
| Molecular Formula | C10H10ClF2N |
| Molecular Weight | 217.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(S)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1270069-76-5), molecular formula C10H10ClF2N and molecular weight 217.64 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, (S)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClF2N |
| Molecular Weight | 217.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- (S)-2-(4-chloro-3,5-difluorophenyl)pyrrolidine (CAS 1212832-34-2)
- (R)-2-(4-chloro-3,5-difluorophenyl)pyrrolidine (CAS 1213068-61-1)
- (R)-(4-Chloro-3,5-difluorophenyl)(cyclopropyl)methanamine (CAS 1213170-92-3)
- (R)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241679-60-6)
- (R)-2-(3-chloro-2,4-difluorophenyl)pyrrolidine (CAS 1241679-62-8)
- (S)-2-(4-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241679-75-3)
- (S)-2-(3-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1241680-70-5)
- (S)-2-(3-chloro-2,6-difluorophenyl)pyrrolidine (CAS 1241681-59-3)
Recommended Standards
- (S)-2-(4-chloro-2,5-difluorophenyl)pyrrolidine (CAS 1269780-39-3)
- (R)-2-(2-chloro-4,5-difluorophenyl)pyrrolidine (CAS 1270093-56-5)
- (S)-2-(2-chloro-3,6-difluorophenyl)pyrrolidine (CAS 1241682-70-1)
- (R)-2-(4-chloro-2,5-difluorophenyl)pyrrolidine (CAS 1270179-13-9)
- 2-Bromo-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1264130-85-9)
- 1-Benzyl-5-methyl-1H-indole-3-carbonitrile (CAS 1334159-63-5)
- N-Methyl-2-piperidinemethanol-d5 (CAS 1794971-17-7)
- 1-(Boc-amino)-2,3-butadiene (CAS 92136-43-1)
- N-(Azido-PEG4)-N-Boc-PEG4-Boc (CAS 2112737-20-7)
- 1-(2,6-Dimethylpyrimidin-4-yl)-N-propylpiperidin-4-amine dihydrochloride (CAS 1306605-11-7)
- Ethyl 4-amino-5-mesityl-1-methyl-1H-pyrazole-3-carboxylate (CAS 203870-53-5)
- Mal-amido-PEG12-propionic Acid (CAS 871133-36-7)
- (2S)-2-(Bromomethyl)-8-(4-chlorophenoxy)-2-hydroxy-octanoic Acid (S)-2-Bromomethyl-2-hydroxy-8-(4-chlorophenoxy)octanoic Acid 467235-27-4 (CAS 467235-27-4)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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