Enzalutamide Impurity 2 CAS 1242137-16-1
| CAS No. | 1242137-16-1 |
| Molecular Formula | C20H14F4N4O2S |
| Molecular Weight | 450.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Enzalutamide Impurity 2 (C20H14F4N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Enzalutamide Impurity 2 (CAS 1242137-16-1, C20H14F4N4O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Enzalutamide Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14F4N4O2S |
| Molecular Weight | 450.41 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity 26 (CAS 2029195-97-7)
- Enzalutamide Impurity 31 (CAS CATO-C4X-101631)
- Enzalutamide Impurity 1 (CAS 1242137-15-0)
- Enzalutamide Impurity 3 (CAS 1242137-18-3)
- Enzalutamide Impurity 16 (CAS 915087-16-0)
- Enzalutamide Impurity 43 (CAS CATO-C4X-101643)
- Enzalutamide (CAS 915087-33-1)
- Enzalutamide Impurity 9 (CAS 1802242-43-8)
Recommended Standards
- Aripiprazole Quinolinediol Impurity (CAS 1391054-74-2)
- Ponatinib Impurity 60 (CAS CATO-C4X-226960)
- Dacarbazine Lactose Adduct Impurity (CAS CATO-C4X-23054)
- Bendroflumethiazide Impurity 1 (CAS CATO-C4X-33521)
- Lemborexant Impurity 30 (CAS CATO-C4X-304230)
- Indobufen Impurity 82 (CAS CATO-C4X-179282)
- Dabigatran Impurity 111 (CAS CATO-C4X-1089111)
- 4-Methoxynaphthalen-1-amine (CAS 16430-99-2)
- 1-(2,5-Dichlorobenzyl)piperidin-3-ol (CAS 1289386-65-7)
- 1-Oxa-8-azaspiro[4.5]decane, 2,2-dimethyl- (CAS 374794-94-2)
- 2,4,6-Trifluorobenzyl methacrylate (CAS 1820739-95-4)
- tert-Butyl (4-aminopyrimidin-2-yl)carbamate (CAS 262295-93-2)
- D-Selenocystine (CAS 26932-45-6)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com