Enzalutamide Impurity 16 CAS 915087-16-0
| CAS No. | 915087-16-0 |
| Molecular Formula | C21H17F3N4O2S |
| Molecular Weight | 446.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Enzalutamide Impurity 16 (CAS 915087-16-0), a pharmacopoeial impurity reference standard (molecular formula C21H17F3N4O2S, MW 446.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Enzalutamide Impurity 16 (C21H17F3N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H17F3N4O2S |
| Molecular Weight | 446.45 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity 3 (CAS 1242137-18-3)
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- Enzalutamide Impurity 2 (CAS 1242137-16-1)
- Enzalutamide Impurity 1 (CAS 1242137-15-0)
- Enzalutamide Impurity 43 (CAS CATO-C4X-101643)
- Enzalutamide (CAS 915087-33-1)
- Enzalutamide Impurity 9 (CAS 1802242-43-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com