Ethyl 4-amino-5,8-difluoroquinoline-3-carboxylate CAS 1242260-57-6
| CAS No. | 1242260-57-6 |
| Molecular Formula | C12H10F2N2O2 |
| Molecular Weight | 252.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 4-amino-5,8-difluoroquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 4-amino-5,8-difluoroquinoline-3-carboxylate (CAS 1242260-57-6), molecular formula C12H10F2N2O2 and molecular weight 252.22 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 4-amino-5,8-difluoroquinoline-3-carboxylate (C12H10F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 252.22 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10F2N2O2 |
| Molecular Weight | 252.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (Z)-4-(3,5-Difluoro-4-hydroxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one (CAS 1241390-29-3)
- 4-ACetylamino-3-methyl-5-nitro-benzoic acid methyl ester (CAS 1263818-07-0)
- 4-(3-Hydroxypyrrolidin-1-yl)-3-nitrobenzoic acid (CAS 1220027-85-9)
- Dimethyl 2-hydroxy-2,3-dihydrobenzofuran-4,6-dicarboxylate (CAS 1268024-07-2)
- tert-butyl 3-(trifluoroacetamido)piperidine-4-carboxylate (CAS 1909319-36-3)
- (R)-3-amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid hcl (CAS 712321-33-0)
- 3-Amino-4-iodobenzonitrile (CAS 665033-21-6)
- (S)-1-Cbz-2-methylpiperazine (CAS 923565-98-4)
- (2e)-3-(2-Nitrophenyl)prop-2-en-1-ol (CAS 130489-97-3)
- 4'-Pentyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 59662-47-4)
- 2-(1H-Indol-1-yl)propanoic acid (CAS 131488-64-7)
- tert-Butyl methyl(5-nitropyridin-2-yl)carbamate (CAS 1039055-45-2)
- Z-Pyr-OtBu (CAS 81470-51-1)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
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