(Z)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(dimethylamino)acrylonitrile CAS 1242271-46-0
| CAS No. | 1242271-46-0 |
| Molecular Formula | C11H9ClF3N3 |
| Molecular Weight | 275.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(Z)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(dimethylamino)acrylonitrile (CAS 1242271-46-0), molecular formula C11H9ClF3N3 and molecular weight 275.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (Z)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(dimethylamino)acrylonitrile (C11H9ClF3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), (Z)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(dimethylamino)acrylonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9ClF3N3 |
| Molecular Weight | 275.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
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- 7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine, 97% (CAS 1254981-30-0)
- 2-[(5-chloro-2-fluorophenyl)formamido]-3-hydroxybutanoic acid (CAS 1396969-18-8)
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- 3-Chloro-N-methyl-N-(1H-pyrrol-1-yl)-5-(trifluoromethyl)pyridin-2-amine (CAS 338400-00-3)
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- N-(3-chloro-2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 478261-68-6)
Recommended Standards
- 1-(2-Chlorobenzyl)-3-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 1245808-40-5)
- N-(5-Chloro-6-((2-hydroxyethyl)amino)-3-nitropyrazin-2-yl)acetamide (CAS 87591-65-9)
- 4-(4-Chlorophenyl)-2-methyl-5-(trifluoromethyl)-2,3-dihydro-1h-pyrazol-3-imine (CAS 1365630-37-0)
- 8-Chloro-10-oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acid (CAS 74163-11-4)
- 5-chloro-4-ethoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 2384302-77-4)
- Ethyl 4-bromo-1-isobutyl-1H-pyrazole-3-carboxylate (CAS 1856021-12-9)
- 4-Mercaptobenzene-1,2-diol (CAS 27320-22-5)
- 3',5',N2-Tri-O-acetyl 2'-Deoxyguanosine (CAS 193092-29-4)
- 1-(7-Chloro-3-methylbenzo[b]thien-2-yl)ethanone (CAS 38056-11-0)
- 1-BRomo-3-n-butyloxy-4-methoxybenzene (CAS 1823899-42-8)
- 1,1-Dimethoxyoctane (CAS 10022-28-3)
- 4-Bromo-2-cyano-5-(difluoromethyl)benzoic acid (CAS 1807073-34-2)
- Methyl 5-(pyrrolidin-1-yl)pyrazine-2-carboxylate (CAS 944133-94-2)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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