5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione CAS 893736-17-9
| CAS No. | 893736-17-9 |
| Molecular Formula | C14H7ClFNO2 |
| Molecular Weight | 275.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 275.66 g/mol gives 5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione (CAS 893736-17-9) is a high-purity analytical reference standard with the molecular formula C14H7ClFNO2 and a molecular weight of 275.66 g/mol.
Based on its molecular formula C14H7ClFNO2, 5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 275.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H7ClFNO2 |
| Molecular Weight | 275.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2,2’,4,4’-Tetrahydroxydiphenyl Sulfide (CAS 97-29-0)
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- (S)-2-Amino-N-(4-(N-methylacetamido)cyclohexyl)propanamide (CAS 1354020-12-4)
- 1-Benzyl-1h-pyrrole-3-carbonitrile (CAS 1233659-29-4)
- Ethyl 6-methyl-2-(4-((2-methylpiperidin-1-yl)sulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride (CAS 1216670-71-1)
- 7-Hydroxyfuro[4,3,2-de]chromen-4(3H)-one (CAS 1177271-53-2)
- 2-((4-(Tert-pentyl)cyclohexyl)amino)ethan-1-ol (CAS 1039974-37-2)
- Dodecanedinitrile (CAS 4543-66-2)
- (R)-1-((benzyloxy)carbonyl)-5-oxopiperidine-2-carboxylic acid (CAS 2306249-10-3)
- Peptide 440 (CAS CATO-CPTD788440)
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