5-(3-Bromophenyl)picolinic acid CAS 1242340-03-9
| CAS No. | 1242340-03-9 |
| Molecular Formula | C12H8BrNO2 |
| Molecular Weight | 278.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3-Bromophenyl)picolinic acid (CAS 1242340-03-9), molecular formula C12H8BrNO2 and molecular weight 278.10 g/mol, is a CATO reference standard with documented purity and traceability.
5-(3-Bromophenyl)picolinic acid (C12H8BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8BrNO2 |
| Molecular Weight | 278.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- 3-(3-Bromophenyl)picolinic acid (CAS 1344701-75-2)
- 5-(2-Bromophenyl)nicotinic acid (CAS 887973-35-5)
- 5-(3-Bromophenyl)nicotinic acid (CAS 924854-21-7)
- 5-(4-Bromophenyl)nicotinic Acid (CAS 887973-36-6)
- 5-(4-Bromophenyl)picolinic acid (CAS 945836-05-5)
- 6-(2-Bromophenyl)nicotinic acid (CAS 887976-25-2)
- N-[2-(4-Bromophenyl)ethyl]-2,2-difluoroacetamide (CAS 1010422-42-0)
- 1-(3-Bromophenyl)-4-oxocyclohexane-1-carbonitrile (CAS 1202006-92-5)
Recommended Standards
- 4-Bromo-5-(3-isocyanatophenyl)-1-methyl-1H-pyrazole (CAS 1206969-04-1)
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- 4-Bromo-N-(pyrazin-2-yl)benzamide (CAS 1154240-14-8)
- 5-Bromo-2-(1H-pyrazol-4-yl)isoindolin-1-one (CAS 1315544-56-9)
- 898761-34-7 3-(4-Bromophenyl)-4'-chloropropiophenone MFCD03843367 (CAS 898761-34-7)
- H-allo-Thr(tBu)-OH (CAS 201353-89-1)
- 1,4-Dithiaspiro[4.5]Decan-8-ol (CAS 22428-86-0)
- 6-Methoxy-3-methyl-benzo[b]thiophene-2-carboxylic acid methyl ester (CAS 82788-18-9)
- 4-Chloro-6-(4-fluorophenyl)thieno[3,2-d]pyrimidine (CAS 681260-56-0)
- (E)-4-((2-chlorobenzyl)thio)-3-nitrobenzaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 303996-05-6)
- 5-Methyl-4-propyl-4H-1,2,4-triazole-3-thiol (CAS 121519-86-6)
- 3-[([1,1-Biphenyl]-2-yloxy)methyl]pyrrolidinehydrochloride (CAS 1220028-54-5)
- Ethyl 4-Bromo-5-methyl-2-nitrobenzoate (CAS 1805600-33-2)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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