4-(tert-Butyl)-3-hydroxy-N-methylbenzamide CAS 1243355-52-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1243355-52-3
Molecular FormulaC12H17NO2
Molecular Weight207.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(tert-Butyl)-3-hydroxy-N-methylbenzamide CAS 1243355-52-3 chemical structure

Description

The occurrence of 4-(tert-Butyl)-3-hydroxy-N-methylbenzamide is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(tert-Butyl)-3-hydroxy-N-methylbenzamide (CAS 1243355-52-3), molecular formula C12H17NO2 and molecular weight 207.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(tert-Butyl)-3-hydroxy-N-methylbenzamide (C12H17NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(tert-Butyl)-3-hydroxy-N-methylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H17NO2
Molecular Weight207.27 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms1

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