6-(Benzyloxy)-8-(trifluoromethyl)-1H-purin-2-amine CAS 160948-29-8
| CAS No. | 160948-29-8 |
| Molecular Formula | C13H10F3N5O |
| Molecular Weight | 309.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-(Benzyloxy)-8-(trifluoromethyl)-1H-purin-2-amine (C13H10F3N5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-(Benzyloxy)-8-(trifluoromethyl)-1H-purin-2-amine (CAS 160948-29-8), a certified reference material (molecular formula C13H10F3N5O, MW 309.25 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Benzyloxy)-8-(trifluoromethyl)-1H-purin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N5O |
| Molecular Weight | 309.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Benzyloxy Standards
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Recommended Standards
- (3S)-1-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}pyrrolidin-3-ol (CAS 1206641-40-8)
- 6-((2-(Trifluoromethyl)benzyl)oxy)-1H-purin-2-amine (CAS 168098-98-4)
- n-[4-cyano-5-methyl-2-oxo-3-(trifluoromethyl)-2,3-dihydro-1h-pyrrol-3-yl]benzamide (CAS 634175-98-7)
- 5-(5-Methoxy-2-(trifluoromethyl)-1H-benzo-[d]imidazol-1-yl)pyrazin-2-amine (CAS 950845-99-5)
- (E)-[2-(4-Chlorobenzenesulfonyl)ethylidene][(2,6-dichlorophenyl)methoxy]amine (CAS 338395-19-0)
- Tris(2-ethylhexyl) 2,2',2''-((methylstannanetriyl)tris(sulfanediyl))triacetate (CAS 57583-34-3)
- (3-Bromo-4-propoxyphenyl)methanol (CAS 915922-40-6)
- N-Benzyl-3-(1H-indol-2-yl)-1H-pyrazole-4-carboxamide (CAS 827316-53-0)
- 3-Indazol-1-yl-propylamine (CAS 933744-08-2)
- 1-(3'-Chlorosulfonyl-4'-methoxyphenyl)-1-propanone (CAS 932896-41-8)
- N-(2-(methylthio)phenyl)methanesulfonamide (CAS 4907-98-6)
- 1-(4-Fluorophenyl)piperidine-2-carboxylic acid (CAS 1504689-74-0)
- 5-Fluoro-2-oxa-7-azaspiro[3.5]Nonane (CAS 2091478-15-6)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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