3-Cyclopropoxy-5-(trifluoromethyl)benzenesulfonamide CAS 1243357-52-9
| CAS No. | 1243357-52-9 |
| Molecular Formula | C10H10F3NO3S |
| Molecular Weight | 281.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.25 g/mol gives 3-Cyclopropoxy-5-(trifluoromethyl)benzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Cyclopropoxy-5-(trifluoromethyl)benzenesulfonamide (CAS 1243357-52-9) is a high-purity analytical reference standard with the molecular formula C10H10F3NO3S and a molecular weight of 281.25 g/mol.
The molecular framework of 3-Cyclopropoxy-5-(trifluoromethyl)benzenesulfonamide (C10H10F3NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10F3NO3S |
| Molecular Weight | 281.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Cyclopropoxy Standards
- 3-Cyclopropoxy-2-(trifluoromethyl)benzenesulfonamide (CAS 1243285-43-9)
- 4-Cyclopropoxy-2-(trifluoromethyl)benzenesulfonamide (CAS 1243383-67-6)
- 2-Cyclopropoxy-4-(trifluoromethyl)benzenesulfonamide (CAS 1243397-52-5)
- 4-Cyclopropoxy-3-(trifluoromethyl)benzenesulfonamide (CAS 1243454-02-5)
- 5-Cyclopropoxy-6-(trifluoromethyl)pyridine-2-sulfonamide (CAS 1243323-79-6)
- 5-Cyclopropoxy-3-(trifluoromethyl)pyridine-2-sulfonamide (CAS 1243363-09-8)
- 5-Cyclopropoxy-2-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1243363-36-1)
- 5-Cyclopropoxy-4-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1243386-19-7)
Recommended Standards
- Ethyl 2-(6,8-difluoro-2-methyl-4-oxoquinolin-1(4H)-yl)acetate (CAS 1215515-98-2)
- Methyl (6-methoxy-4-(trifluoromethyl)-pyridin-2-ylsulfanyl)acetate (CAS 1053657-54-7)
- Bis(indenyl)vanadium(II) (CAS 101834-69-9)
- BD 1063-d8 Dihydrochloride (CAS 1246819-69-1)
- 1-(6-Chloropyridin-3-yl)cyclobutane-1-carboxylic acid (CAS 1260666-35-0)
- Diphenyl((phenylsulfinyl)methyl)phosphine oxide (CAS 87762-75-2)
- 6,6'-DIsulfanediyldihexan-1-amine dihydrochloride (CAS 118077-46-6)
- 6-(3,4-Difluorophenyl)pyridin-3-amine (CAS 1225914-71-5)
- 3-Benzyl-6-hydroxy-7-methoxyquinazolin-4(3H)-one (CAS 808793-56-8)
- Acipimox Impurity 5 (CAS 874-54-4)
- Boc-3,5-Dimethyl-L-Tyrosine (CAS 1212941-74-6)
- 4-(Bromomethyl)-9-chloroacridine (CAS 15971-23-0)
- 1-(2-Furylmethyl)-5-oxo-3-pyrrolidinecarbohydrazide (CAS 939230-90-7)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com