Acipimox Impurity 5 CAS 874-54-4
| CAS No. | 874-54-4 |
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Acipimox Impurity 5 (CAS 874-54-4, C5H4N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Acipimox Impurity 5 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 140.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Acipimox Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Acipimox Standards
Recommended Standards
- Vonoprazan Impurity 133 (CAS 15128-82-2)
- 2-Hydroxy-4-nitropyridine 4-Nitro-2-pyridinol 4-Nitropyrid-2-one 4487-51-8 (CAS 4487-51-8)
- 3-Nitropyridin-4-ol (CAS 5435-54-1)
- Trans-3-(trifluoromethyl)cyclobutanol (CAS 2091782-60-2)
- Luliconazole impurity 26 (CAS CATO-C4X-285326)
- Cariprazine Impurity 63 (CAS CATO-C4X-240863)
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- 2-(2-Methoxyethyl)-1,3-dimethylbenzene (CAS 65848-79-5)
- Resiniferonol 9,13,14-Orthophenylacetate (CAS 57852-42-3)
- 3-Bromo-5-(methylsulfonyl)-4H-1,2,4-triazole hydrochloride (CAS 2361643-87-8)
- (S)-3-amino-2-((benzyloxy)methyl)propan-1-ol (CAS 1394891-60-1)
- 3-(Boc-amino)-1-[(tert-butyldimethylsilyl)oxy]-2-propanone (CAS 184429-84-3)
- methyl cis-3-amino-1-fluoro-cyclobutanecarboxylate;hydrochloride (CAS 2231665-97-5)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com