Ethyl 2-chloro-5-(chlorosulfonyl)thiophene-3-carboxylate CAS 1245643-45-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1245643-45-1
Molecular FormulaC7H6Cl2O4S2
Molecular Weight289.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 2-chloro-5-(chlorosulfonyl)thiophene-3-carboxylate CAS 1245643-45-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-chloro-5-(chlorosulfonyl)thiophene-3-carboxylate.

CATO supplies Ethyl 2-chloro-5-(chlorosulfonyl)thiophene-3-carboxylate (CAS 1245643-45-1), a certified reference material (molecular formula C7H6Cl2O4S2, MW 289.16 g/mol) for analytical method development and quality control.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 2-chloro-5-(chlorosulfonyl)thiophene-3-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 289.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H6Cl2O4S2
Molecular Weight289.16 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl-containing
Sulfur Atoms2

Related Ethyl Standards

Recommended Standards

Why CATO?