6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline CAS 34790-74-4

Purity 97%+In StockPharmaceutical Standards
CAS No.34790-74-4
Molecular FormulaC15H10Cl2N2
Molecular Weight289.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline CAS 34790-74-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline.

CATO supplies 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline (CAS 34790-74-4), a certified reference material (molecular formula C15H10Cl2N2, MW 289.16 g/mol) for analytical method development and quality control.

6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline (C15H10Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H10Cl2N2
Molecular Weight289.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Halogen ContentCl-containing
Nitrogen Atoms2

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