[1-(difluoromethyl)-1H-pyrazol-5-yl]methanol CAS 1245772-28-4
| CAS No. | 1245772-28-4 |
| Molecular Formula | C5H6F2N2O |
| Molecular Weight | 148.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[1-(difluoromethyl)-1H-pyrazol-5-yl]methanol (CAS 1245772-28-4), molecular formula C5H6F2N2O and molecular weight 148.11 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, [1-(difluoromethyl)-1H-pyrazol-5-yl]methanol (C5H6F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 148.11 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6F2N2O |
| Molecular Weight | 148.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoromethyl Standards
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5(4H)-one (CAS 1048018-91-2)
- 5-(Difluoromethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 121303-75-1)
- (1-(Difluoromethyl)-1H-pyrazol-3-yl)methanol (CAS 1245772-78-4)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5-ol (CAS 129922-58-3)
- (5-(Difluoromethyl)furan-2-yl)methanol (CAS 152932-54-2)
- 5-(Difluoromethyl)-1-methyl-1H-1,2,4-triazol-3-amine (CAS 1785198-29-9)
- [5-(Difluoromethyl)-1,2-oxazol-3-yl]methanamine (CAS 1896928-61-2)
- (3-(Difluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 2254338-42-4)
Recommended Standards
- 3-(1,1-difluoroethyl)-1,2-oxazol-5-amine (CAS 1188909-17-2)
- Ethyl 4,4-difluorobut-2-ynoate (CAS 129922-56-1)
- L-Lyxono-1,4-lactone (CAS 104196-15-8)
- (2s)-2-hydroxyglutaric acid (2s)-2-hydroxypentanedioic acid (s)-2-hydroxyglutaric acid (s)-alpha-hydroxyglutaric acid 13095-48-2 L-2-hydroxyglutaric acid l-2-hydroxyglutarate l-alpha-hydroxyglutaric acid (CAS 13095-48-2)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-amine (CAS 1182804-44-9)
- 4-Benzyltetrahydro-2H-pyran-2-ol (CAS 71280-30-3)
- 1-Methylpiperidine 1-Oxide (CAS 17206-00-7)
- Methyl(3-propoxyphenyl)sulfane (CAS 178987-12-7)
- Methyl 5-(2-fluorophenyl)isoxazole-3-carboxylate (CAS 668970-74-9)
- (R)-2-Butyramido-3-methylbutanoic acid (CAS 143896-77-9)
- m-PEG9-azide (CAS 1354521-95-1)
- 2-(4-Methoxyphenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 932841-53-7)
- 4-Chloro-2-(2-((6-nitrobenzo[d]thiazol-2-yl)thio)acetamido)benzoic acid (CAS 730965-99-8)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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