1-(2-Chloro-6-nitrophenyl)-4-methyl-1h-pyrazole CAS 1245772-33-1
| CAS No. | 1245772-33-1 |
| Molecular Formula | C10H8ClN3O2 |
| Molecular Weight | 237.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(2-Chloro-6-nitrophenyl)-4-methyl-1h-pyrazole (CAS 1245772-33-1) is a high-purity analytical reference standard with the molecular formula C10H8ClN3O2 and a molecular weight of 237.64 g/mol.
1-(2-Chloro-6-nitrophenyl)-4-methyl-1h-pyrazole (C10H8ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN3O2 |
| Molecular Weight | 237.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-5-cyclopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011354-08-7)
- 2-Chloro-8-methoxyquinoline-3-carboxylic acid (CAS 1017157-83-3)
- 6-Chloro-4-hydroxy-2-methylquinoline-3-carboxylic acid (CAS 103566-34-3)
- 1-(3-Chloro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042534-76-8)
- 1-(3-Chloro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042604-53-4)
- 2-Chloro-6-hydroxy-7-methoxyquinoline-3-carbaldehyde (CAS 1046138-52-6)
- Methyl 8-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1065074-57-8)
- 2-(8-Chloro-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1092288-62-4)
Recommended Standards
- (2-chloro-3-formyl-1H-indol-5-yl) acetate (CAS 1233354-97-6)
- Methyl 2-Amino-4-chloroquinazoline-7-carboxylate (CAS 1246209-90-4)
- 7-Chloro-2-hydroxy-6-methoxyquinoline-3-carbaldehyde (CAS 1225335-03-4)
- 2-(3-Chloro-4-methylphenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1247419-45-9)
- 2-Amino-5-trifluoromethyl-1,3,4-oxadiazole 5-(trifluoromethyl)-1,3,4-oxadiazol-2-amine 5-trifluoromethyl-1,3,4-oxadiazol-2-ylamine 768-29-6 (CAS 768-29-6)
- Methyl 2-amino-3-(6-fluoro-1h-indol-3-yl)propanoate hydrochloride (CAS 1018815-57-0)
- 2-Chloro-5-hydroxy-6-methylpyrimidin-4(1H)-one (CAS 62022-09-7)
- 5-Methyl-3-(phenylmethylene)-2(3H)-furanone (CAS 165263-76-3)
- 2-Pyridinecarboxylic acid, 5-methyl-, 1-oxide (CAS 31283-69-9)
- 3-Chloro-6-hydroxypicolinic acid (CAS 68160-46-3)
- Procaterol Impurity 28 (CAS 59828-06-7)
- (2-Fluoro-4-((4-oxopiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704064-22-1)
- N-(3-bromobenzyl)tetrahydrofuran-3-amine (CAS 1342883-31-1)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com