Procaterol Impurity 28 CAS 59828-06-7
| CAS No. | 59828-06-7 |
| Molecular Formula | C15H20N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Procaterol Impurity 28.
Procaterol Impurity 28 (CAS 59828-06-7) is a certified pharmaceutical impurity reference standard with the molecular formula C15H20N2O3HCl and a molecular weight of 312.79 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Procaterol Impurity 28 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O3 HCl |
| Molecular Weight | 312.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Procaterol Standards
- Procaterol Impurity 11 (CAS 103-01-5)
- Procaterol Impurity 19 (CAS 103702-26-7)
- Procaterol Impurity N7 (CAS 15450-72-3)
- Procaterol Impurity N2 (CAS 15572-56-2)
- Procaterol Impurity 15 (CAS 22614-69-3)
- Procaterol Impurity 1 (CAS 59827-93-9)
- Procaterol Impurity 41 (CAS 59828-07-8)
- Hydrochloride Procaterol (CAS 62929-91-3)
Recommended Standards
- Levocabastine impurity 26 (CAS CATO-C4X-228926)
- Risdiplam Impurity 3 (CAS CATO-C4X-30123)
- Xylometazoline EP Impurity E Monohydrate (CAS 6192-52-5)
- (4-Methoxytetrahydrofuran-3-yl)amine hydrochloride (CAS 1955561-02-0)
- 2-((Tert-butoxycarbonyl)amino)-2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)acetic acid (CAS 1822544-80-8)
- 1-(2,4-Dichlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-71-5)
- (3-Phenyl-5,6-dihydro-4h-1,2,4-oxadiazin-6-yl)methanol (CAS 56493-85-7)
- (S)-Methyl 2-amino-3-cyclopentylpropanoate hydrochloride (CAS 1191996-99-2)
- 3-Chloro-2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-5-(trifluoromethyl)pyridine (CAS 735319-95-6)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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