7-Phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid CAS 1245808-60-9
| CAS No. | 1245808-60-9 |
| Molecular Formula | C14H8F3N3O2 |
| Molecular Weight | 307.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 7-Phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1245808-60-9), a certified reference material (molecular formula C14H8F3N3O2, MW 307.23 g/mol) for analytical method development and quality control.
7-Phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (C14H8F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N3O2 |
| Molecular Weight | 307.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Phenyl Standards
- 5-Phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1018125-41-1)
- 3-(4-(3-(Trifluoromethyl)phenyl)pyridin-2-yl)-1,2,4-oxadiazol-5(4H)-one (CAS 1219453-92-5)
- 3-(4-(2-(Trifluoromethyl)phenyl)pyridin-2-yl)-1,2,4-oxadiazol-5(4H)-one (CAS 1219453-93-6)
- 7-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 1423026-63-4)
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanecarbonitrile (CAS 162781-04-6)
- 1-(3,5-Bis(trifluoromethyl)phenyl)-2,5-dimethyl-1H-pyrrole (CAS 175205-51-3)
- 2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione (CAS 448230-37-3)
- 5-Phenyl-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-2-carboxylic acid (CAS 294194-47-1)
Recommended Standards
- 6-Morpholin-4-yl-3-nitro-4-(trifluoromethyl)-pyridin-2-ylhydrazine (CAS 1305712-08-6)
- 5-Nitro-3-(2-(trifluoromethyl)phenyl)-1H-indazole (CAS 1356087-76-7)
- 2-Bromo-6-(2-ethylbutoxy)naphthalene (CAS 1092346-54-7)
- 5-Nitro-3-(4-(trifluoromethyl)phenyl)-1H-indazole (CAS 1356087-78-9)
- 2,5-Dibromo-3-fluorobenzoyl chloride (CAS 1806353-77-4)
- 2-Isopropyl-3,5,6-trimethylpyrazine (CAS 104638-10-0)
- 4-(4-Piperidinyloxy)benzoic acid hydrochloride (CAS 1609396-09-9)
- 5-(3,4-Dimethoxybenzyl)-4-(4-phenoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 380431-16-3)
- 3-bromo-5-(4-fluorophenyl)-1,2,4-oxadiazole (CAS 1564477-82-2)
- 2-(2-(2-Bromo-4-(2-phenylpropan-2-yl)phenoxy)ethyl)piperidine hydrochloride (CAS 1219967-16-4)
- Sodium 5-bromo-2-hydroxybenzoate (CAS 37717-99-0)
- 5-Pyrimidineboronic Acid Pinacol Ester (CAS 321724-19-0)
- Cis-2-methylenehexahydrofuro[2,3-b]furan (CAS 88938-71-0)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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