2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione CAS 448230-37-3
| CAS No. | 448230-37-3 |
| Molecular Formula | C14H8F3N3O2 |
| Molecular Weight | 307.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 307.23 g/mol gives 2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione (CAS 448230-37-3) is a high-purity analytical reference standard with the molecular formula C14H8F3N3O2 and a molecular weight of 307.23 g/mol.
Structurally, 2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione (C14H8F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 307.23 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[5-(trifluoromethyl)pyridin-2-yl]-1,2,3,4-tetrahydrophthalazine-1,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N3O2 |
| Molecular Weight | 307.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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- 7-Phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1245808-60-9)
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Recommended Standards
- 3-(Azepan-1-ylmethyl)-5-bromo-1H-indole (CAS 1893174-21-4)
- 4-(Adamantan-1-yl)-2-bromophenol (CAS 63013-55-8)
- 3-(Azepan-1-ylmethyl)-6-bromo-1H-indole (CAS 1893157-32-8)
- 5-Nitro-3-(3-(trifluoromethyl)phenyl)-1H-indazole (CAS 395099-31-7)
- Boceprevir-d9 (CAS 1256751-11-7)
- Ethyl 4-Isopropyl-4-piperidinecarboxylate Hydrochloride (CAS 1186663-19-3)
- Titanium, bis(η5-2,4-cyclopentadien-1-yl)[ethanedioato(2-)-κO1,κO2]- (CAS 78966-09-3)
- 2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole (CAS 16502-01-5)
- N-Cyclohexylbenzo[d]thiazole-2-sulfonamide (CAS 16170-33-5)
- Methyl 6-bromo-3-nitrobenzofuran-2-carboxylate (CAS 1956321-90-6)
- 2,5-Dimethyl-1-(2,2,4-trimethyl-2,3-dihydro-1-benzofuran-7-yl)-1H-pyrrole (CAS 866008-60-8)
- tert-Butyl ((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)methyl)carbamate (CAS 1235451-39-4)
- 2-cyano-3-azabicyclo[3.1.0]hexane (CAS 115182-91-7)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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