27-hydroxycholesterol (D6) CAS 1246302-95-3
| CAS No. | 1246302-95-3 |
| Molecular Formula | - |
| Molecular Weight | 408.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
27-hydroxycholesterol (D6) (CAS 1246302-95-3), molecular formula C27H40D6O2 and molecular weight 408.69 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C27H40D6O2, 27-hydroxycholesterol (D6) contains deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H40D6O2 |
| Molecular Weight | 408.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related hydroxycholesterol Standards
- 25-Hydroxycholesterol-26,26,26,27,27,27-d6 (CAS 88247-69-2)
- 22(S)-hydroxycholesterol-d7 (CAS 1246302-91-9)
- 22(R)-hydroxycholesterol-d7 (CAS 1246302-93-1)
- 24(RS)-Hydroxycholesterol-25,26,26,26,27,27,27-d7 (CAS 144154-78-9)
- 7β-Hydroxycholesterol-25,26,26,26,27,27,27-d7 (CAS 349553-97-5)
- 7α-Hydroxycholesterol-d7 (CAS 349553-94-2)
- 26- Hydroxycholesterol (CAS 13095-61-9)
- 4β-Hydroxycholesterol (CAS 17320-10-4)
Recommended Standards
- 2-Propenoic acid, 3-[3,4-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-, (2E) (CAS 203118-32-5)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(3-(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-37-5)
- 1 4-BIS(TRIETHOXYSILYL)BENZENE 1,4-bis(triethoxysilyl)benzene 2615-18-1 (CAS 2615-18-1)
- 5'-Amino-4-bromo-4''-chloro-[1,1':3',1''-terphenyl]-4',6'-dicarbonitrile (CAS 299937-34-1)
- 7-(2-(4-(3-Chlorophenyl)piperazin-1-yl)-2-oxoethoxy)-4-methyl-2H-chromen-2-one (CAS 742116-89-8)
- 2-Cyclopropyl-1,3-benzoxazol-5-amine (CAS 1017027-77-8)
- 3-(Morpholin-2-yl)propanoic acid (CAS 1367717-32-5)
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- Dexamethasone Sodium Phosphate Impurity 47 (CAS CATO-C4X-116547)
- 8-Chloro-2-(chloromethyl)quinolin-4-ol (CAS 946692-43-9)
- 2-(Piperidin-4-ylidene)ethan-1-ol (CAS 849701-22-0)
- 4-(1H-1,2,3-Triazol-1-yl)phenylboronic Acid Pinacol Ester (CAS 1101174-00-8)
- 6-Bromo-4-hydrazinylquinazoline (CAS 307529-02-8)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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