8-Chloro-2-(chloromethyl)quinolin-4-ol CAS 946692-43-9
| CAS No. | 946692-43-9 |
| Molecular Formula | C10H7Cl2NO |
| Molecular Weight | 228.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Chloro-2-(chloromethyl)quinolin-4-ol (C10H7Cl2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 8-Chloro-2-(chloromethyl)quinolin-4-ol (CAS 946692-43-9), a certified reference material (molecular formula C10H7Cl2NO, MW 228.07 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro-2-(chloromethyl)quinolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2NO |
| Molecular Weight | 228.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-3-(chloromethyl)quinolin-2(1H)-one (CAS 1017127-45-5)
- 7-Chloro-3-(chloromethyl)quinolin-2(1H)-one (CAS 1017161-81-7)
- 2-Chloro-1-(6-chloro-1h-indol-3-yl)ethan-1-one (CAS 1018637-67-6)
- 2-Chloro-1-(5-chloro-1H-indol-2-yl)ethan-1-one (CAS 1799477-12-5)
- 2-Chloro-1-methyl-1H-indole-3-carbonyl chloride (CAS 67342-12-5)
- 3-Chloro-2-(chloromethyl)quinolin-4-ol (CAS 856100-78-2)
- 6-Chloro-2-(chloromethyl)-4(1H)-quinolinone (CAS 946784-67-4)
- 3-Chloro-4-(4-chloro-1h-pyrazol-1-yl)aniline (CAS 1006959-51-8)
Recommended Standards
- 8-Amino-5,7-dichloro-2-naphthalenol (CAS 497151-50-5)
- Dibenzothiophene-2-boronic Acid (CAS 668983-97-9)
- 7,8-Dichloro-2-methylquinolin-4-ol (CAS 203626-50-0)
- 312693-16-6 3-Methoxybenzylzinc chloride, 0.5M in tetrahydrofuran MFCD01319883 (CAS 312693-16-6)
- 1-(1-(4-Fluorophenyl)ethyl)piperidin-4-ol (CAS 1146080-10-5)
- (S)-10-(5-((1-Methylpyrrolidin-2-yl)methoxy)pyridin-3-yl)dec-9-yn-1-ol (CAS 820231-81-0)
- 1-(5-Bromopyridin-2-yl)cyclobutane-1-carboxylic acid hydrochloride (CAS 2138531-01-6)
- Venlafaxine Impurity 16 (CAS 6547-53-1)
- 1-(5-Bromo-4-methylpyridin-2-yl)ethan-1-one (CAS 1413285-68-3)
- (R)-2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid (CAS 134235-82-8)
- tert-Butyl 4-(6-chloro-2-(methylthio)pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate (CAS 1261231-27-9)
- Bupropion (S)-Isomer Hydrochloride (CAS 324548-45-0)
- 2-{[4-(Aminocarbonyl)anilino]carbonyl}cyclohexanecarboxylic acid (CAS 353765-97-6)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com