5-Cyclopropyl-4-fluoro-1H-pyrazol-3-amine CAS 1246384-89-3
| CAS No. | 1246384-89-3 |
| Molecular Formula | C6H8FN3 |
| Molecular Weight | 141.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Cyclopropyl-4-fluoro-1H-pyrazol-3-amine is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Cyclopropyl-4-fluoro-1H-pyrazol-3-amine (CAS 1246384-89-3) is a high-purity analytical reference standard with the molecular formula C6H8FN3 and a molecular weight of 141.15 g/mol.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 5-Cyclopropyl-4-fluoro-1H-pyrazol-3-amine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 141.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8FN3 |
| Molecular Weight | 141.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropyl Standards
- 1-Cyclopropyl-5-fluoro-1H-pyrazol-4-amine (CAS 1892571-60-6)
- 1-Cyclopropyl-2-azetidinecarboxylic acid (CAS 1042381-95-2)
- N-Cyclopropyl-3-oxobutanamide (CAS 110262-87-8)
- 5-Cyclopropyl-morpholin-3-one (CAS 1260667-89-7)
- 1-Cyclopropyl-4-hydroxypyrrolidin-2-one (CAS 1340512-90-4)
- (3-Cyclopropyl-4,5-dihydro-1,2-oxazol-5-yl)methanol (CAS 1343591-10-5)
- Cyclopropyl(isoxazolidin-2-yl)methanone (CAS 154082-24-3)
- 5-Cyclopropyl-1,2,4-thiadiazol-3-amine (CAS 1342142-02-2)
Recommended Standards
- 3-Fluoro-6-hydrazinyl-2-methylpyridine (CAS 1208250-43-4)
- n-Ethyl-5-fluoropyrimidin-2-amine (CAS 1289386-10-2)
- (R)-1-(5-fluoropyrimidin-2-yl)ethan-1-amine (CAS 1202352-14-4)
- 3-Fluoro-2-hydrazineyl-4-methylpyridine (CAS 1314932-46-1)
- 2-Methyl-3-Heptanone (CAS 13019-20-0)
- 2-(Methylthio)-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS 867353-58-0)
- 5-Methoxy-4-methylbenzene-1,3-diol (CAS 55382-24-6)
- Ethyl (R)-3,7-Dimethyl-6-octenoate (CAS 65620-73-7)
- Milrinone Impurity 22 (CAS 717818-05-8)
- 2-(3,5-Difluoro-4-iodophenyl)-1,3-dioxolane (CAS 357166-63-3)
- 2-{[(1-benzyl-1H-pyrazol-4-yl)methyl]amino}ethan-1-ol hydrochloride (CAS 1311314-38-1)
- 5-(4-Bromo-2-chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 1157455-35-0)
- Venetoclax Impurity 40 (CAS CATO-C4X-249540)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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