8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-thia-4,8-diazaspiro[4.5]Decan-3-one CAS 1246738-29-3
| CAS No. | 1246738-29-3 |
| Molecular Formula | C13H13ClF3N3OS |
| Molecular Weight | 351.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-thia-4,8-diazaspiro[4.5]Decan-3-one (CAS 1246738-29-3), molecular formula C13H13ClF3N3OS and molecular weight 351.78 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-thia-4,8-diazaspiro[4.5]Decan-3-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 351.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-thia-4,8-diazaspiro[4.5]Decan-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13ClF3N3OS |
| Molecular Weight | 351.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-(((5-Chloro-2-methoxyphenyl)amino)methylene)-1,5-dioxaspiro[5.5]undecane-2,4-dione (CAS 370843-64-4)
- 4-(2-Chloro-6-fluorobenzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylic acid (CAS 688760-38-5)
- 6-(2-Chloro-4-fluorophenyl)-4-methyl-2-(thiazol-2-yl)-1,6-dihydropyrimidine-5-carboxylic acid (CAS 361161-78-6)
- 5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one (CAS 861070-76-0)
- 6-Chloro-N-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1040662-93-8)
- 4-Chloro-5-nitro-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 1421338-17-1)
- (1-(3-Chloro-4-fluorophenyl)-1H-1,2,3-triazol-4-yl)(naphthalen-2-yl)methanone (CAS 685107-11-3)
- 1-((2-Chloro-5-nitrophenyl)sulfonyl)-2-methyl-1H-benzo[d]imidazole (CAS 337506-43-1)
Recommended Standards
- Eicosanoic-d39 Acid (CAS 39756-32-6)
- 4-([1,1'-Biphenyl]-2-carboxamido)-2-chlorobenzoic acid (CAS 180340-01-6)
- 2,4,6-Tribromo-3,5-difluoropyridine (CAS 30841-93-1)
- 1-(4-Chlorophenyl)-5-(4-fluorophenyl)-3-(methylsulfonyl)-1H-1,2,4-triazole (CAS 99793-75-6)
- N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 (CAS 2107273-62-9)
- Methyl 3-[2-(dimethylsulfamoyl)phenyl]-5-fluorobenzoate (CAS 1820734-79-9)
- 2-Methyl-1-(3-methylbenzyl)-1h-indole-3-carbaldehyde (CAS 592550-45-3)
- 2,2,2-Trifluoro-1-(4-methoxynaphthalen-1-yl)ethan-1-amine (CAS 1038378-96-9)
- 8-Methyl-1-thia-4-azaspiro[4.5]Decane (CAS 31404-03-2)
- 4-Fluoro-3-[(4-fluorophenyl)(hydroxy)methyl]phenylboronic acid (CAS 2377587-42-1)
- 4-[4-(hydroxymethyl)phenoxy]butanenitrile (CAS 125439-56-7)
- 2-((2-Chloroethoxy)methyl)oxirane (CAS 5412-14-6)
- 5-[(4-Fluorophenyl)sulfanyl]-3,6-diphenyl-1,2,4-triazine (CAS 339013-10-4)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com