5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one CAS 861070-76-0
| CAS No. | 861070-76-0 |
| Molecular Formula | C20H14ClNO3 |
| Molecular Weight | 351.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 351.78 g/mol gives 5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one (CAS 861070-76-0) is a high-purity analytical reference standard with the molecular formula C20H14ClNO3 and a molecular weight of 351.78 g/mol.
5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one (C20H14ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14ClNO3 |
| Molecular Weight | 351.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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