Meclizine-d8 Dihydrochloride CAS 1246816-06-7
| CAS No. | 1246816-06-7 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Meclizine-d8 Dihydrochloride is closely related to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Meclizine-d8 Dihydrochloride (CAS 1246816-06-7) is a high-purity analytical reference standard with the molecular formula C25H19D8ClN2HCl and a molecular weight of 435.46 g/mol.
Based on its molecular formula C25H19D8ClN2HCl, Meclizine-d8 Dihydrochloride contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 435.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H19D8ClN2 2*HCl |
| Molecular Weight | 435.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Meclizine Standards
- Meclizine Dihydrochloride (CAS 1104-22-9)
- Meclizine N-Oxide (CAS 114624-69-0)
- Meclizine N,N'-Dioxide (CAS 114624-70-3)
- Meclizine Impurity N1 DiHCl (CAS 115291-60-6)
- Meclizine-d8 DiHCl (CAS 1432062-16-2)
- Meclizine Impurity 14 (CAS 299460-62-1)
- Meclizine Dihydrochloride Monohydrate (CAS 31884-77-2)
- Meclizine Hydrochloride (CAS 410538-37-3)
Recommended Standards
- N,N,2,2-Tetramethylpyrrolidin-3-amine (CAS 1152111-28-8)
- 1-Methoxyisoquinoline-4-carbonitrile (CAS 87954-16-3)
- rac Bendroflumethiazide (CAS 73-48-3)
- N-(2-bromophenethyl)acetamide (CAS 74315-08-5)
- 2-(1-(Phenylthio)cyclopropyl)but-3-en-2-ol (CAS 41596-96-7)
- 6-Methylchroman-4-amine hydrochloride (CAS 191608-11-4)
- n-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1048647-68-2)
- (±)-Tetrahydrojatrorrhizine (CAS 27313-86-6)
- N,N-Dimethyl-1-(pyridin-3-yl)methanamine 2055-21-2 (CAS 2055-21-2)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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