Chlorphenamine EP Impurity A CAS 1246816-57-8
| CAS No. | 1246816-57-8 |
| Molecular Formula | C16H24ClN3 |
| Molecular Weight | 293.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Chlorphenamine EP Impurity A (CAS 1246816-57-8, C16H24ClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H24ClN3, Chlorphenamine EP Impurity A contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 293.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Chlorphenamine EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24ClN3 |
| Molecular Weight | 293.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorphenamine Standards
- Chlorphenamine impurity 54 (CAS CATO-C4X-118854)
- Chlorphenamine Impurity 7 (CAS 78180-89-9)
- Chlorphenamine impurity 57 (CAS CATO-C4X-118857)
- Chlorphenamine EP Impurity D (CAS 65676-21-3)
- Chlorphenamine impurity 50 (CAS CATO-C4X-118850)
- Chlorphenamine Impurity 73 (CAS CATO-C4X-118873)
- Chlorphenamine Impurity 62 (CAS CATO-C4X-118862)
- Chlorphenamine Oxide (CAS CATO-C4X-118833)
Recommended Standards
- 4-(4-Chloro-2-cyclohexylphenoxy)piperidine (CAS 367501-21-1)
- Pitolisant impurity 19 (CAS CATO-C4X-252019)
- 4-Chloro-7-(heptan-4-yl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 192129-45-6)
- 4-Bromo-2-fluoro-3-methoxy-6-nitrophenylboronic acid (CAS 2377606-74-9)
- Edaravone Impurity 25 (CAS 92-43-3)
- Pivmecillinam EP Impurity A (CAS 25031-08-7 (free base))
- Cinacalcet Impurity 94 (CAS CATO-C4X-105994)
- 6-Methoxy-1H-indazole-5-boronic acid (CAS 2408429-67-2)
- (5-Methoxy-2-(trifluoromethyl)phenyl)methanol (CAS 1261682-03-4)
- 1-(3,4-Dimethoxybenzyl)-5-oxopyrrolidine-3-carbonitrile (CAS 1017398-00-3)
- tert-butyl (2S)-2-methyl-5-oxopyrrolidine-2-carboxylate (CAS 882392-64-5)
- Clenisopenterol Hydrochloride (CAS 1435935-00-4)
- PC Azido-PEG3-NHS carbonate ester (CAS 1802907-96-5)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com