Emtricitabine Impurity N2 CAS 1246819-86-2
| CAS No. | 1246819-86-2 |
| Molecular Formula | C9H12FN3O2S2 |
| Molecular Weight | 277.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Emtricitabine Impurity N2 (CAS 1246819-86-2, C9H12FN3O2S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H12FN3O2S2, Emtricitabine Impurity N2 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 277.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Emtricitabine Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12FN3O2S2 |
| Molecular Weight | 277.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Emtricitabine Standards
- Emtricitabine impurity 44 (CAS CATO-C4X-123244)
- Emtricitabine Impurity 32 (CAS 145032-08-2)
- Emtricitabine Impurity 31 (CAS 151722-06-4)
- Emtricitabine impurity 45 (CAS 161683-20-1)
- Emtricitabine Ring-opening Impurity (CAS CATO-C4X-123212)
- Emtricitabine Impurity 60 (CAS CATO-C4X-123260)
- Emtricitabine Impurity 24 (CAS 1160303-44-5)
- Emtricitabine S-oxide(Mixture) (CAS 152128-77-3)
Recommended Standards
- 1-Amino-3-phenyl-8H-indeno[1,2-c]thiophen-8-one (CAS 1245739-66-5)
- n-(4-Hydroxyphenyl)-n,4-dimethylbenzene-1-sulfonamide (CAS 124772-05-0)
- 1242902-54-0 1-(3-Fluorobenzyl)-3-piperidin-4-ylimidazolidin-2-one MFCD15732380 (CAS 1242902-54-0)
- 2-((3-Ethylphenyl)amino)pyridine-3-sulfonamide (CAS 1251573-85-9)
- Cefpirome Impurity 42 (CAS CATO-C4X-120742)
- Epalrestat impurity 35 (CAS CATO-C4X-223635)
- Amlodipine Impurity N22 (CAS 39562-06-6)
- 6-Methylindoline (CAS 86911-82-2)
- 2'-(3-(Trifluoromethyl)phenyl)spiro[thiochromane-3,5'-[1,3]dioxan]-4-one (CAS 339028-94-3)
- 1-(Cyclopropylmethyl)-4-iodopyrazole (CAS 1340571-52-9)
- (E)-1-(2,6-Dihydroxy-3,4-dimethoxyphenyl)-3-phenylprop-2-en-1-one (CAS 42438-78-8)
- 6-Chloro-5,7-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1267773-12-5)
- 1-(2-Ethoxyphenyl)-3-(1-ethyl-1H-indol-3-yl)urea (CAS 922940-34-9)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com