Eltrombopag Methyl Ester CAS 1246929-01-0
| CAS No. | 1246929-01-0 |
| Molecular Formula | C26H24N4O4 |
| Molecular Weight | 456.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Eltrombopag Methyl Ester.
Eltrombopag Methyl Ester (CAS 1246929-01-0), molecular formula C26H24N4O4 and molecular weight 456.49 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C26H24N4O4, Eltrombopag Methyl Ester contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 456.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H24N4O4 |
| Molecular Weight | 456.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Eltrombopag Standards
- Eltrombopag Impurity 24 (CAS 1437383-35-1)
- Eltrombopag Impurity 46 (CAS CATO-C4X-119846)
- Eltrombopag Impurity 93 (CAS CATO-C4X-119893)
- Eltrombopag N-Oxide Impurity (CAS CATO-C4X-11981)
- Eltrombopag Impurity 155 (CAS CATO-C4X-1198155)
- Eltrombopag Impurity 45 (CAS CATO-C4X-119845)
- Eltrombopag Impurity 120 (CAS CATO-C4X-1198120)
- Eltrombopag Impurity 7 (CAS 1428987-69-2)
Recommended Standards
- 264273-08-7 [(1S)-4-Amino-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-oxo-1,3,4,5-tetrahydro-2H-2-benzazepin-2-yl]acetic acid DTXSID30725193 (CAS 264273-08-7)
- Methyl 5-((4-ethoxyphenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335406-28-5)
- Cefuroxime Impurity 88 (CAS CATO-C4X-124588)
- Methyl 5-((2-fluorophenyl)carbamoyl)-4-methyl-2-(2-(o-tolyloxy)acetamido)thiophene-3-carboxylate (CAS 335410-72-5)
- 2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline (CAS 146578-99-6)
- (1R,4R)-5,5-Difluoro-2-azabicyclo[2.2.1]heptane hydrochloride (CAS 2306247-79-8)
- 2H-Indazole, 5-bromo-2-methyl-3-(1-methylethyl)- (CAS 1528976-72-8)
- 2,4-Dibromo-6-chloro-3-methylaniline (CAS 1195139-59-3)
- 2-(3-Bromo-5-(methylsulfonyl)phenyl)propan-2-ol (CAS 1897390-95-2)
- 2-Methyl-4-phenylbutan-2-amine (CAS 43052-72-8)
- [(2,3-dimethoxyphenyl)methyl][3-(1H-imidazol-1-yl)propyl]amine (CAS 940200-82-8)
- 2-(Difluoromethyl)-3-methoxy-6-(trifluoromethoxy)pyridine-5-acetic acid (CAS 1806022-19-4)
- (5,8-difluoro-3-quinolyl) acetate (CAS 2435612-19-2)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
Why CATO?
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