3-Fluoro-4-(3-hydroxypiperidin-1-yl)benzonitrile CAS 1247085-74-0
| CAS No. | 1247085-74-0 |
| Molecular Formula | C12H13FN2O |
| Molecular Weight | 220.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Fluoro-4-(3-hydroxypiperidin-1-yl)benzonitrile (CAS 1247085-74-0), a certified reference material (molecular formula C12H13FN2O, MW 220.24 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Fluoro-4-(3-hydroxypiperidin-1-yl)benzonitrile is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 220.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13FN2O |
| Molecular Weight | 220.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 2-Fluoro-4-(piperidin-3-yloxy)benzonitrile (CAS 1063734-68-8)
- 10-Fluoro-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (CAS 1082914-61-1)
- 4-Fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1178903-32-6)
- 6-Fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1178903-34-8)
- 6-Fluoro-2-(pyrrolidin-3-yl)isoindolin-1-one (CAS 1206969-88-1)
- 3-(2-Fluoro-6-(pyrrolidin-1-yl)pyridin-3-yl)prop-2-yn-1-ol (CAS 1228666-51-0)
- 4-(5-Fluoro-1H-indol-3-yl)butanamide (CAS 1256348-67-0)
- 5-Fluoro-2-(3-hydroxypiperidin-1-yl)benzonitrile (CAS 1260803-70-0)
Recommended Standards
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- 5-(4-Fluorophenyl)-2-(propan-2-yl)-2,3-dihydro-1h-pyrazol-3-one (CAS 1221725-83-2)
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