Abacavir EP Impurity C CAS 124752-25-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.124752-25-6
Molecular FormulaC11H14N6O
Molecular Weight246.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Abacavir EP Impurity C CAS 124752-25-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 246.27 g/mol gives Abacavir EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Abacavir EP Impurity C (CAS 124752-25-6) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14N6O and a molecular weight of 246.27 g/mol.

The molecular framework of Abacavir EP Impurity C (C11H14N6O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Abacavir EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14N6O
Molecular Weight246.27 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Nitrogen Atoms6

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