2-(3-amino-1H-pyrazol-1-yl)-5-chlorobenzonitrile CAS 1249223-99-1
| CAS No. | 1249223-99-1 |
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(3-amino-1H-pyrazol-1-yl)-5-chlorobenzonitrile (CAS 1249223-99-1), molecular formula C10H7ClN4 and molecular weight 218.64 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3-amino-1H-pyrazol-1-yl)-5-chlorobenzonitrile (C10H7ClN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related amino Standards
- 4-(3-Amino-1h-pyrazol-1-yl)-3-chlorobenzonitrile (CAS 1343126-68-0)
- 2-Amino-5-(4-chlorophenyl)furan-3-carbonitrile (CAS 26454-85-3)
- 3-amino-5-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 42754-62-1)
- 3-Amino-5-chloro-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 62208-83-7)
- 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 64096-89-5)
- 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 51516-68-8)
- 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-3-carbonitrile (CAS 460331-57-1)
- 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 51516-67-7)
Recommended Standards
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- 1-(2-Aminophenyl)-5-chloro-1H-pyrazole-4-carbonitrile (CAS 1269291-00-0)
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