5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile CAS 51516-67-7
| CAS No. | 51516-67-7 |
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (C10H7ClN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 51516-67-7) is a high-purity analytical reference standard with the molecular formula C10H7ClN4 and a molecular weight of 218.64 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-(3-amino-1H-pyrazol-1-yl)-5-chlorobenzonitrile (CAS 1249223-99-1)
- 4-(3-Amino-1h-pyrazol-1-yl)-3-chlorobenzonitrile (CAS 1343126-68-0)
- 2-Amino-5-(4-chlorophenyl)furan-3-carbonitrile (CAS 26454-85-3)
- 3-amino-5-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 42754-62-1)
- 3-Amino-5-chloro-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 62208-83-7)
- 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 64096-89-5)
- 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 51516-68-8)
- 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-3-carbonitrile (CAS 460331-57-1)
Recommended Standards
- 6-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 89479-57-2)
- 6-Chloro-2-(furan-2-yl)-1H-benzo[d]imidazole (CAS 83330-29-4)
- 6-Chloro-2-(furan-2-yl)imidazo[1,2-a]pyridine (CAS 904818-13-9)
- 5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline (CAS 61164-87-2)
- Methyl 2-[(2-{[2,4-dichloro-5-(2-methoxyethoxy)phenyl]carbamoyl}-2-hydroxy-2-methylethyl)sulfanyl]benzoate (CAS 866136-35-8)
- N,N-Diisopropyl-4h-benzo[d][1,3,2]dioxaborinin-2-amine (CAS 791785-37-0)
- 2-(Octylamino)-4,5-dihydro-1,3-thiazol-4-one (CAS 30686-80-7)
- 5-Amino-2-(octyloxy)benzoic acid (CAS 13737-93-4)
- 5-(2-(Hydroxymethyl)phenyl)pyrimidin-2-ol (CAS 1111104-11-0)
- Fasudil Impurity 20 (CAS CATO-C4X-136520)
- 6-Cyclopropyl-2-imino-2,3-dihydropyrimidin-4(1h)-one (CAS 21573-08-0)
- 3-((1h-Benzo[d]imidazol-1-yl)methyl)benzimidamide dihydrochloride (CAS 1221722-72-0)
- (1-(tert-butoxycarbonyl)-5-(2-(piperidin-1-yl)ethoxy)-1H-indol-2-yl)boronic acid (CAS 913388-68-8)
- Peptide Impurity 05 (CAS 2322924-83-2)
Why CATO?
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