1-(5-Chloro-2-fluorobenzyl)piperazine CAS 1251127-61-3
| CAS No. | 1251127-61-3 |
| Molecular Formula | C11H14ClFN2 |
| Molecular Weight | 228.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(5-Chloro-2-fluorobenzyl)piperazine (CAS 1251127-61-3), molecular formula C11H14ClFN2 and molecular weight 228.69 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H14ClFN2, 1-(5-Chloro-2-fluorobenzyl)piperazine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 228.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H14ClFN2 |
| Molecular Weight | 228.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-cyclohexylamino-3-fluoropyridine (CAS 1020253-24-0)
- 1-[(2-Chloro-4-fluorophenyl)methyl]piperazine (CAS 118630-33-4)
- (2-Chloro-6-fluorophenyl)(cyclopentyl)methanol (CAS 1225687-12-6)
- 1-[(3-Chloro-2-fluorophenyl)methyl]piperazine (CAS 1240565-18-7)
- 1-[(4-Chloro-3-fluorophenyl)methyl]piperazine (CAS 1240572-89-7)
- 1-(2-Chloro-4-fluorobenzyl)pyrrolidin-3-amine (CAS 1247243-31-7)
- (3-Chloro-4-fluorophenyl)(cyclopentyl)methanol (CAS 1339640-22-0)
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Recommended Standards
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- methyl 6-(chlorosulfonyl)hexanoate (CAS 1202760-84-6)
- 1-(3-Chloro-5-fluorophenyl)hexan-1-one (CAS 1352206-93-9)
- 4-Aminothieno[2,3-d]pyrimidine-2(1h)-thione (CAS 177355-92-9)
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- Methyl 2-(2-chlorothiazol-5-yl)acetate (CAS 1424352-59-9)
- (S)-N-((1-(2-Aminoethyl)pyrrolidin-2-yl)methyl)-N-methylacetamide (CAS 1354017-35-8)
- 2-Hydroxy-5-(morpholine-4-sulfonyl)benzoic acid (CAS 91134-85-9)
- Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate (CAS 78775-33-4)
- Xantifibrate - API Standards (CAS 36921-54-7)
- 2-(ethylamino)-N-(2-methoxyphenyl)acetamide (CAS 900641-64-7)
- 1-((3S,4R)-3-Hydroxy-2,2-dimethyl-6,7-bis-oxazol-2-yl-chroman-4-yl)-3-phenyl-urea (CAS 1222671-22-8)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
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