6-Chloro-3-(cyclopropylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 1251290-43-3
| CAS No. | 1251290-43-3 |
| Molecular Formula | C9H9ClN4 |
| Molecular Weight | 208.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-3-(cyclopropylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1251290-43-3) is a high-purity analytical reference standard with the molecular formula C9H9ClN4 and a molecular weight of 208.65 g/mol.
The molecular framework of 6-Chloro-3-(cyclopropylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine (C9H9ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-3-(cyclopropylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClN4 |
| Molecular Weight | 208.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-cyclobutyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094292-72-4)
- 6-Chloro-3-(2-methylcyclopropyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094292-73-5)
- 2-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrazine (CAS 1133082-92-4)
- 5-Chloro-6-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1135283-22-5)
- 2-Chloro-5-methyl-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine (CAS 1202986-04-6)
- 3-Chloro-6-methyl-4-(1-methyl-1h-imidazol-2-yl)pyridazine (CAS 1209062-25-8)
- 3-Chloro-6-(4,5-dimethyl-1H-imidazol-1-yl)pyridazine (CAS 1248926-89-7)
- 4-Chloro-3-(1-methyl-1h-1,2,4-triazol-5-yl)aniline (CAS 1249590-54-2)
Recommended Standards
- 2-Chloro-3-(3,5-dimethyl-1H-pyrazol-1-yl)pyrazine (CAS 1249644-27-6)
- 3-(Azetidin-1-yl)-8-chloroimidazo[1,5-a]pyrazine (CAS 1326280-68-5)
- 4-Chloro-2,5-dimethyl-6-(1H-pyrazol-1-yl)pyrimidine (CAS 1339677-70-1)
- 2-Chloro-4-(4-methyl-4H-1,2,4-triazol-3-yl)aniline (CAS 1341922-98-2)
- (3-Boc-amino-pyrrolidin-1-yl)-naphthalen-2-yl-acetic acid (CAS 885275-87-6)
- 2-(((2-Hydroxyethyl)thio)methyl)quinazolin-4(1H)-one (CAS 874606-65-2)
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- n-(Cyclohexylmethyl)-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-5-amine (CAS 1152642-87-9)
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