N-(2,5-difluorophenyl)-2-(2-oxo-5-(piperidin-1-ylsulfonyl)pyridin-1(2H)-yl)acetamide CAS 1251608-21-5
| CAS No. | 1251608-21-5 |
| Molecular Formula | C18H19F2N3O4S |
| Molecular Weight | 411.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2,5-difluorophenyl)-2-(2-oxo-5-(piperidin-1-ylsulfonyl)pyridin-1(2H)-yl)acetamide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2,5-difluorophenyl)-2-(2-oxo-5-(piperidin-1-ylsulfonyl)pyridin-1(2H)-yl)acetamide (CAS 1251608-21-5) is a high-purity analytical reference standard with the molecular formula C18H19F2N3O4S and a molecular weight of 411.42 g/mol.
Based on its molecular formula C18H19F2N3O4S, N-(2,5-difluorophenyl)-2-(2-oxo-5-(piperidin-1-ylsulfonyl)pyridin-1(2H)-yl)acetamide contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 411.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19F2N3O4S |
| Molecular Weight | 411.42 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 1-(2,4-Difluorophenyl)-3-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}pyrrolidine-2,5-dione (CAS 329059-09-8)
- N-(2,4-Difluorophenyl)-1,3-dimethyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazole-4-carboxamide (CAS 303997-89-9)
- N-(2,4-Difluorophenyl)-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]benzamide (CAS 321430-17-5)
- N-(2,4-difluorophenyl)-3-((3-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide (CAS 344273-05-8)
- N-(2,4-Difluorophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577962-34-6)
- N-(3,4-Difluorophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-59-1)
- N-(2,5-Difluorophenyl)-2-[5-(morpholine-4-sulfonyl)-2-oxo-1,2-dihydropyridin-1-yl]acetamide (CAS 1251573-91-7)
- N-(2,4-Difluorophenyl)-2-[5-(morpholine-4-sulfonyl)-2-oxo-1,2-dihydropyridin-1-yl]acetamide (CAS 1251676-57-9)
Recommended Standards
- (2E)-3-(Naphthalen-2-yl)-1-{4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}prop-2-en-1-one (CAS 1025257-57-1)
- 1-Benzyl-6,7-difluoro-3-(phenylsulfonyl)quinolin-4(1H)-one (CAS 899213-86-6)
- 2-((4-Oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(4-((trifluoromethyl)thio)phenyl)acetamide (CAS 1022421-80-2)
- 2-((3-Cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(4-fluorobenzyl)acetamide (CAS 664999-24-0)
- 2-(3-Iodobenzamido)thiophene-3-carboxamide (CAS 1089991-72-9)
- 1-(4-Carbamoylbenzenesulfonyl)piperidine-4-carboxylic acid (CAS 923212-38-8)
- 1-((4-Bromo-2-fluorophenyl)sulfonyl)-4-ethylpiperazine (CAS 1331185-87-5)
- 1-Ethyl-4-ethynylpiperidine (CAS 2138386-85-1)
- 6-(3-(4-Chlorophenyl)ureido)pyridazine-3-carboxamide (CAS 87977-06-8)
- 5-(Aminomethyl)-n-ethylpyridine-2-sulfonamide (CAS 1463425-12-8)
- (2R,3R,4R,5R,6R)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-ethynyltetrahydro-2H-pyran (CAS 219864-05-8)
- 2-Oxo-5-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 787640-16-8)
- tert-Butyl N-(5-methyl-1,3-thiazol-2-yl)carbamate (CAS 1186298-92-9)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
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