1-(2-((4-Chlorophenyl)amino)-2-oxoethyl)-N-cyclopropyl-2-oxo-1,2-dihydroquinoxaline-6-carboxamide CAS 1251675-06-5
| CAS No. | 1251675-06-5 |
| Molecular Formula | C20H17ClN4O3 |
| Molecular Weight | 396.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(2-((4-Chlorophenyl)amino)-2-oxoethyl)-N-cyclopropyl-2-oxo-1,2-dihydroquinoxaline-6-carboxamide (CAS 1251675-06-5), a certified reference material (molecular formula C20H17ClN4O3, MW 396.83 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-((4-Chlorophenyl)amino)-2-oxoethyl)-N-cyclopropyl-2-oxo-1,2-dihydroquinoxaline-6-carboxamide (C20H17ClN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17ClN4O3 |
| Molecular Weight | 396.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
- 1-((3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)methyl)-3-isopropylquinazoline-2,4(1H,3H)-dione (CAS 1105197-19-0)
- (4-Chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin-1-yl)methanone (CAS 115687-05-3)
- 2-(6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)acetic acid (CAS 1260530-42-4)
- 2-(4-(2-(2-Chlorophenyl)acetamido)phenyl)-N-cyclopropyl-2H-tetrazole-5-carboxamide (CAS 1396767-72-8)
- 3-(3-(4-Chlorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid (CAS 777857-53-1)
- Methyl 2-(4-(3-(4-chlorophenyl)ureido)phenoxy)benzoate (CAS 865660-46-4)
- 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-6-cyclopropyl-4-(trifluoromethyl)nicotinonitrile (CAS 625377-46-0)
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Recommended Standards
- 4-(1-(2-Amino-5-chloropyrimidin-4-yl)indolin-6-yl)-2-(3-methyl-1,2,4-oxadiazol-5-yl)but-3-yn-2-ol (CAS 1202761-77-0)
- 6-Chloro-2-oxo-N-[1-(phenylmethyl)-1H-pyrazol-5-yl]-3(2H)-benzoxazolepropanamide (CAS 1177727-04-6)
- Molibresib carboxylic acid, >98% (HPLC) (CAS 1300019-38-8)
- Metyltetraprole (CAS 1472649-01-6)
- 2-Chloro-6-(trifluoromethyl)benzoyl chloride (CAS 916420-44-5)
- 3-methylhex-5-yn-3-ol (CAS 19135-01-4)
- 3-Bromo-5-(pentafluoro-λ6-sulfanyl)benzene-1,2-diamine (CAS 1159512-25-0)
- Fmoc-D-Trp(Me)-OH (CAS 168471-22-5)
- 4-Bromo-2-methyl-2H-benzo[d][1,2,3]triazole (CAS 1785385-57-0)
- 6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 5334-35-0)
- N,N-Diethyl-7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338778-31-7)
- 3,4-Dichloro-N-(3-cyano-4-(o-tolylsulfonyl)phenyl)benzamide (CAS 320421-34-9)
- (R)-cyclopropyl(3-fluoro-4-(trifluoromethoxy)phenyl)methanamine (CAS 1213014-31-3)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
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