Ticagrelor EP Impurity A CAS 1251765-07-7
| CAS No. | 1251765-07-7 |
| Molecular Formula | C14H22N6O4S |
| Molecular Weight | 370.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ticagrelor EP Impurity A (CAS 1251765-07-7), a pharmacopoeial impurity reference standard (molecular formula C14H22N6O4S, MW 370.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ticagrelor EP Impurity A (C14H22N6O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ticagrelor EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H22N6O4S |
| Molecular Weight | 370.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 81 (CAS CATO-C4X-109381)
- Ticagrelor Impurity 9 (CAS 1445580-43-7)
- Ticagrelor Impurity 82 (CAS 220241-60-1)
- Ticagrelor Impurity 192 (CAS 1628472-93-4)
- Ticagrelor Impurity 10 (CAS 1402150-32-6)
- Ticagrelor impurity 169 (CAS CATO-C4X-1093169)
- Ticagrelor Impurity 111 (CAS 220352-29-4)
- Ticagrelor Impurity 67 (CAS CATO-C4X-109367)
Recommended Standards
- N,N-Dimethyl-4-{[(5-oxo-3-phenyl-1,5-dihydro-4H-pyrazol-4-yliden)methyl]amino}benzenesulfonamide (CAS 320415-75-6)
- Lubiprostone Impurity 29 (CAS CATO-C4X-113629)
- Ethyl 3-oxo-4-((3-(p-tolyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanoate (CAS 852376-09-1)
- Cephalexin-d5 Hydrate (CAS CATO-CCHM703163)
- Sotagliflozin Impurity 3 (CAS CATO-C4X-30043)
- Mirogabalin Impurity 157 (CAS CATO-C4X-2924157)
- Ambroxol Impurity 49 HCl (CAS CATO-C4X-108549)
- 3-Amino-n-methylbenzene-1-sulfonamide hydrochloride (CAS 1170865-45-8)
- 2,4,5-Trichloro-N-(5-iodopyridin-2-yl)benzene-1-sulfonamide (CAS 338401-06-2)
- 3,5,7-Tribromo-4-methyl-1H-indazole (CAS 1000341-05-8)
- Cyclobutyl(2-methoxyphenyl)methanamine (CAS 1337605-33-0)
- 3,5-Difluoro-4-nitrobenzodifluoride (CAS 1803786-80-2)
- (5-Methoxy-1-(pyrimidin-2-yl)-1H-indol-3-yl)methanol (CAS 1092346-13-8)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com