(4-(1-(2-Methoxy-3-(trifluoromethyl)-[1,1-biphenyl]-4-carbonyl)azetidin-3-yl)piperazin-1-yl)(thiazol-2-yl)methanone CAS 1252771-06-4
| CAS No. | 1252771-06-4 |
| Molecular Formula | C26H25F3N4O3S |
| Molecular Weight | 530.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(1-(2-Methoxy-3-(trifluoromethyl)-[1,1-biphenyl]-4-carbonyl)azetidin-3-yl)piperazin-1-yl)(thiazol-2-yl)methanone (C26H25F3N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(4-(1-(2-Methoxy-3-(trifluoromethyl)-[1,1-biphenyl]-4-carbonyl)azetidin-3-yl)piperazin-1-yl)(thiazol-2-yl)methanone (CAS 1252771-06-4), molecular formula C26H25F3N4O3S and molecular weight 530.56 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25F3N4O3S |
| Molecular Weight | 530.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methoxy Standards
- 2-Methoxy-3-stearamidopropyl (2-(trimethylammonio)ethyl) phosphate xhydrate (CAS 163702-19-0)
- 5-Methoxy-2-methyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl)pyrazolo[1,5-a]pyridine-3-carboxamide (CAS 1799682-71-5)
- N-(2-Methoxy-5-methylphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477330-54-4)
- (E)-2-methoxy-4-((4-oxo-3-(1-phenylethyl)-2-thioxothiazolidin-5-ylidene)methyl)phenyl 4-nitrobenzoate (CAS 374617-50-2)
- a-[[[2-(4-Methoxy-3-methylphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-3-nitro-4-(phenylmethoxy)benzenemethanol (CAS 1616967-23-7)
- 5-((3-(4-Methoxy-3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(4-methylbenzyl)-2-thioxothiazolidin-4-one (CAS 623934-75-8)
- 6-Methoxy-2,2’,4,4’-tetrabromodiphenyl ether (CAS 102739-99-1)
- 2-Methoxy-6-[2-(1-trityl-1H-imidazol-2-yl)-vinyl]-benzoic acid ethyl ester (CAS 365542-38-7)
Recommended Standards
- Dutasteride Impurity 5 (CAS 164656-22-8)
- O,O-(Butane-1,4-diyl) bis(4-hydroxybutyl) Diterephthalate (CAS 29278-67-9)
- BMS-599626 (CAS 714971-09-2)
- CH2COOH-PEG9-CH2COOH (CAS 2250056-46-1)
- Methyl 1-(2,2-difluoroethyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018141-97-3)
- 48042-47-3 Diethyl phosphate DTXSID10872492 (CAS 48042-47-3)
- (9H-Fluoren-9-yl)methyl 3-amino-3-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 951625-98-2)
- 5-Methoxy-1H-indene-1,3(2H)-dione (CAS 17666-95-4)
- 2-Amino-6-hydroxy-2,6-dimethylheptanoic acid (CAS 6169-73-9)
- 2-(4-Chlorophenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile (CAS 142921-23-1)
- 2-[(5-bromopyridin-2-yl)sulfanyl]pyridine-3-carboxylic acid (CAS 1016799-66-8)
- 2-(4-Bromo-1H-pyrazol-1-yl)-4-(trifluoromethyl)pyrimidine (CAS 1215458-83-5)
- 2-Chlorobenzo[d]oxazol-5-amine (CAS 1352912-46-9)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com