(2R)-3-Chloro-2-[[4-(trifluoromethoxy)phenyl]methoxy]propyl ester 4-Methoxybenzoic Acid CAS 1253202-35-5
| CAS No. | 1253202-35-5 |
| Molecular Formula | C19H18ClF3O5 |
| Molecular Weight | 418.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2R)-3-Chloro-2-[[4-(trifluoromethoxy)phenyl]methoxy]propyl ester 4-Methoxybenzoic Acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 418.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(2R)-3-Chloro-2-[[4-(trifluoromethoxy)phenyl]methoxy]propyl ester 4-Methoxybenzoic Acid (CAS 1253202-35-5) is a high-purity analytical reference standard with the molecular formula C19H18ClF3O5 and a molecular weight of 418.79 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18ClF3O5 |
| Molecular Weight | 418.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related R Standards
- 11-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one (CAS 339012-01-0)
- 5-[(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl)amino]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 321432-02-4)
- 4-Chloro-N-[3-(5-(trifluoromethyl)pyridin-2-yl)-[1,2,4]--oxadiazol-5-ylmethyl]benzenesulphonamide (CAS 1311278-40-6)
- 2-Chloro-N-[5-(5-(trifluoromethyl)pyridin-2-yl)--[1,2,4]oxadiazol-3-ylmethyl]benzenesulphonamide (CAS 1311279-94-3)
- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-{[(4-fluorophenyl)methyl]carbamoyl}acetate (CAS 478063-75-1)
- N-(4-chloro-2-fluorophenyl)-3-(4-methoxyphenyl)-3-(2,2,2-trifluoroacetamido)propanamide (CAS 439108-90-4)
- (6-{3-[(4-Chloro-phenyl)-hydrazonomethyl]-phenyl}-4-trifluoromethyl-pyridin-2-yl)-dimethyl-amine (CAS 1311283-91-6)
- (6-{4-[(4-Chloro-phenyl)-hydrazonomethyl]-phenyl}-4-trifluoromethyl-pyridin-2-yl)-dimethyl-amine (CAS 1311283-99-4)
Recommended Standards
- Ethyl 7-amino-2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 303150-39-2)
- 1-(2-(1H-indol-3-yl)ethyl)-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidin-4(1H)-one (CAS 551930-80-4)
- N'-[(1E)-[2-(4-Chlorophenoxy)phenyl]methylidene]-4-(trifluoromethyl)benzohydrazide (CAS 338393-72-9)
- 5-Amino-N-(5-chloro-2-methoxyphenyl)-1-{[(2-fluorophenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide (CAS 901046-29-5)
- 3-Amino-4-fluorophenylboronic Acid Pinacol Ester (CAS 1003575-43-6)
- 2-Chloro-4-methyl-5-nitroaniline (CAS 1081809-78-0)
- N-(1-Acetylindolin-6-yl)-1-(m-tolyl)methanesulfonamide (CAS 1058213-45-8)
- (E)-3-(2,4,6-Trimethylphenyl)-2-propenoic acid ethyl ester (CAS 84001-90-1)
- 4-Benzoyl-3-phenylisoxazol-5(2H)-one (CAS 62094-35-3)
- 2-Chloro-N-(3-isoxazolyl)isonicotinamide (CAS 1211512-04-7)
- 1,1,3,3-Tetramethyl-2-(3-(trimethoxysilyl)propyl)guanidine (CAS 69709-01-9)
- 2-(Thiophen-3-yl)acetamide (CAS 13781-66-3)
- 2-(5-Bromothiophen-2-yl)-2,3-dihydrobenzofuran-5-carbonitrile (CAS 851777-32-7)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com