Pranoprofen Impurity 49 CAS 1254691-84-3
| CAS No. | 1254691-84-3 |
| Molecular Formula | C14H13NO3 |
| Molecular Weight | 243.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pranoprofen Impurity 49.
As a process- or degradation-related impurity, Pranoprofen Impurity 49 (CAS 1254691-84-3, C14H13NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pranoprofen Impurity 49 (C14H13NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pranoprofen Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13NO3 |
| Molecular Weight | 243.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Pranoprofen Standards
- Pranoprofen Impurity 42 (CAS CATO-C4X-181142)
- Pranoprofen Impurity 54 (CAS CATO-C4X-181154)
- Pranoprofen Impurity N3 (CAS 52549-07-2)
- Pranoprofen Impurity 43 (CAS CATO-C4X-181143)
- Pranoprofen Impurity 80 (CAS CATO-C4X-181180)
- Pranoprofen Impurity 81 (CAS CATO-C4X-181181)
- Pranoprofen Impurity 40 (CAS CATO-C4X-181140)
- Pranoprofen Impurity 38 (CAS 53944-40-4)
Recommended Standards
- Ketorolac Impurity 33 (CAS CATO-C4X-166933)
- Varenicline Impurity 16 (CAS 1337563-47-9)
- Ketorolac Impurity 27 (CAS 113502-54-8)
- Varenicline Impurity 58 (CAS CATO-C4X-196258)
- N-nitroso Amlodipine Impurity 149 (CAS CATO-C4X-1095149)
- Nalmefene Impurity 7 (CAS CATO-C4X-12687)
- Terbinafine Impurity 43 (CAS CATO-C4X-133843)
- Ethyl 4-aminopiperidine-1-carboxylate hydrochloride (CAS 53786-43-9)
- Linagliptin Impurity 56 (CAS CATO-C4X-110156)
- 3-Cyclopropoxy-N,4-dimethylbenzamide (CAS 1243468-63-4)
- 3-(2-Fluorophenyl)-5-nitro-1H-indole-2-carbonitrile (CAS 62039-77-4)
- 5,5-Dimethyl-3-((naphthalen-1-ylmethyl)sulfonyl)-4,5-dihydroisoxazole (CAS 834885-15-3)
- 4-(4-Chlorophenyl)-1,3-thiazol-2-ol (CAS 2103-98-2)
- Cycloaspeptide A (CAS 109171-13-3)
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