N-nitroso Amlodipine Impurity 149 CAS CATO-C4X-1095149
| CAS No. | CATO-C4X-1095149 |
| Molecular Formula | C23H28ClN3O8 |
| Molecular Weight | 509.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, N-nitroso Amlodipine Impurity 149 (CAS CATO-C4X-1095149, C23H28ClN3O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of N-nitroso Amlodipine Impurity 149 (C23H28ClN3O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures N-nitroso Amlodipine Impurity 149 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28ClN3O8 |
| Molecular Weight | 509.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-Nitroso Resmetirom impurity 128 (CAS CATO-C4X-2912128)
- N-Nitroso Resmetirom impurity 142 (CAS CATO-C4X-2912142)
- N-Nitroso Resmetirom impurity 143 (CAS CATO-C4X-2912143)
- N-Nitroso Tucatinib 1 (CAS CATO-C4X-260525)
- N-Nitroso Tucatinib 2 (CAS CATO-C4X-260526)
- N-nitroso-mirdametinib (CAS CATO-C4X-34081)
- N-Nitroso Imatinib EP Impurity C (CAS 2816369-80-7)
- N-Nitroso Gentamicin impurity 29 (CAS CATO-C4X-148029)
Recommended Standards
- 1-(2-(2-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)acetyl)-4-(4-methoxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one (CAS 119457-14-6)
- Avanafil Impurity 16 (CAS CATO-C4X-111816)
- Sitafloxacin impurity 88 (CAS CATO-C4X-115588)
- Lenvatinib Impurity 145 (CAS CATO-C4X-1140145)
- Oxfendazole Impurity 1 (CAS 2197014-92-7)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- Lidocaine Impurity 33 (CAS 1374010-02-2)
- 2-Fluoro-5-(thiophen-2-yl)pyridine (CAS 1132832-80-4)
- 6-(Benzyloxy)-1H-indazole (CAS 874668-62-9)
- 3-(((4-Chlorophenyl)thio)methyl)-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 81863-77-6)
- 2,4-Bis(bromomethyl)pyridine (CAS 1003294-47-0)
- Cyclohexyl-d11-methyl Alcohol (CAS 1215077-50-1)
- 3-(2-(3-Cyclohexylureido)thiazol-4-yl)-N-(3-fluorophenyl)propanamide (CAS 1091132-31-8)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com