1-(5-Bromo-2-fluorophenyl)piperidin-2-one CAS 1255574-46-9

Description

Compared with other compounds in its class, the molecular weight of 272.11 g/mol gives 1-(5-Bromo-2-fluorophenyl)piperidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(5-Bromo-2-fluorophenyl)piperidin-2-one (CAS 1255574-46-9) is a high-purity analytical reference standard with the molecular formula C11H11BrFNO and a molecular weight of 272.11 g/mol.

1-(5-Bromo-2-fluorophenyl)piperidin-2-one (C11H11BrFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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