3,3-difluoro-5-(iodomethyl)oxolan-2-one CAS 1256080-97-3
| CAS No. | 1256080-97-3 |
| Molecular Formula | C5H5F2IO2 |
| Molecular Weight | 261.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,3-difluoro-5-(iodomethyl)oxolan-2-one (C5H5F2IO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 3,3-difluoro-5-(iodomethyl)oxolan-2-one (CAS 1256080-97-3), a certified reference material (molecular formula C5H5F2IO2, MW 261.99 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,3-difluoro-5-(iodomethyl)oxolan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5F2IO2 |
| Molecular Weight | 261.99 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
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- 3,5-Difluoro-4-ethoxybenzophenone (CAS 951884-68-7)
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Recommended Standards
- (3-(1,3-Dioxolan-2-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1072946-51-0)
- 2-(2-Bromoacetamido)ethyl dihydrogen phosphate (CAS 52011-43-5)
- 5-Iodo-1-(trifluoromethyl)-1H-pyrazole (CAS 2648965-95-9)
- 5-Bromo-2-hydroxy-3-nitrobenzoic acid (CAS 10169-50-3)
- 2-(Naphthalen-1-yl)propanenitrile (CAS 24168-42-1)
- (4-Isopropylphenyl)methanesulfonyl chloride (CAS 926201-18-5)
- 3-Bromo-4-(1,3-dioxolan-2-yl)benzonitrile (CAS 2586125-79-1)
- 4-(1-Ethyl-1h-1,2,4-triazol-5-yl)butan-2-ol (CAS 1485273-32-2)
- Baricitinib Impurity 95 (CAS 1309430-77-0)
- 2-Ethyl-4,7-difluorobenzofuran-3(2h)-one (CAS 1341917-28-9)
- 3-Indoleboronic Acid Pinacol Ester (CAS 937366-54-6)
- 4-Chloro-N-(3-(hex-1-yn-1-yl)phenyl)benzenesulfonamide (CAS 861209-81-6)
- 5-Methoxy-2-(pyridin-2-yl)aniline (CAS 113623-78-2)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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