2,3-Difluoro-1-methyl-4-(trichloromethoxy)benzene CAS 1404195-01-2
| CAS No. | 1404195-01-2 |
| Molecular Formula | C8H5Cl3F2O |
| Molecular Weight | 261.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 261.48 g/mol gives 2,3-Difluoro-1-methyl-4-(trichloromethoxy)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,3-Difluoro-1-methyl-4-(trichloromethoxy)benzene (CAS 1404195-01-2) is a high-purity analytical reference standard with the molecular formula C8H5Cl3F2O and a molecular weight of 261.48 g/mol.
The molecular framework of 2,3-Difluoro-1-methyl-4-(trichloromethoxy)benzene (C8H5Cl3F2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl3F2O |
| Molecular Weight | 261.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Difluoro Standards
- 1,3-Difluoro-4-methyl-2-(trichloromethoxy)benzene (CAS 1404194-12-2)
- ethyl 2,2-difluoro-2-(7-quinolyl)acetate (CAS 1511535-02-6)
- ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate (CAS 943541-40-0)
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- (R)-1-(3-(1,1-Difluoro-2-methoxy-2-methylpropyl)-2-fluorophenyl)ethan-1-amine (CAS 2842532-89-0)
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Recommended Standards
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- 8-Azaspiro[4.5]decan-1-one (CAS 198133-82-3)
- 2-(But-3-en-2-yl)-1,2,3,4-tetrahydroquinoxaline (CAS 113477-73-9)
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