2-(4-Trifluoromethylphenoxy)pyridine-5-boronic acid CAS 1256358-58-3
| CAS No. | 1256358-58-3 |
| Molecular Formula | C12H9BF3NO3 |
| Molecular Weight | 283.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Trifluoromethylphenoxy)pyridine-5-boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(4-Trifluoromethylphenoxy)pyridine-5-boronic acid (CAS 1256358-58-3), molecular formula C12H9BF3NO3 and molecular weight 283.01 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-Trifluoromethylphenoxy)pyridine-5-boronic acid (C12H9BF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9BF3NO3 |
| Molecular Weight | 283.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethylphenoxy Standards
Recommended Standards
- 7393-43-3 Stannane, tetra-2-propenyl- Tetrallylstannane AI3-28455 EINECS 230-987-5 (CAS 7393-43-3)
- 2-(Difluoromethyl)-5-iodopyridine-3-carboxaldehyde (CAS 1804688-01-4)
- 36132-08-8 5,7-Dibromo-1H-indole 5,7-Dibromoindole (CAS 36132-08-8)
- 4-(Difluoromethyl)-5-iodopicolinaldehyde (CAS 1805129-24-1)
- 2-bromanyl-2,3,3,3-tetrakis(fluoranyl)propanoyl fluoride 2-bromo-2,3,3,3-tetrafluoropropanoyl fluoride 6129-62-0 A833149 (CAS 6129-62-0)
- 2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine (CAS 2792-72-5)
- 2-((2-(Methoxycarbonyl)phenyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate (CAS 876536-10-6)
- 1,1,2,2-Tetrakis(3'-([2,2':6',2''-terpyridin]-4'-yl)-[1,1'-biphenyl]-3-yl)ethene (CAS 2467796-31-1)
- 2,4-Dichloro-N-(5,6-dimethyl-1-(2-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-84-0)
- 2-Chloro-1H-imidazo[4,5-b]pyridine hydrochloride (CAS 132261-24-6)
- Endotoxin Substrate (CAS 68223-96-1)
- 2-(4-(Aminomethyl)-2-(difluoromethyl)-5-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1361813-27-5)
- 1-Butoxy-3-(4-methylpiperazin-1-yl)propan-2-ol dihydrochloride (CAS 1217045-20-9)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com