5-Chloroquinoline-7-carbonitrile CAS 1256463-65-6
| CAS No. | 1256463-65-6 |
| Molecular Formula | C10H5ClN2 |
| Molecular Weight | 188.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloroquinoline-7-carbonitrile (CAS 1256463-65-6) is a high-purity analytical reference standard with the molecular formula C10H5ClN2 and a molecular weight of 188.61 g/mol.
Structurally, 5-Chloroquinoline-7-carbonitrile (C10H5ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 188.61 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-Chloroquinoline-7-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5ClN2 |
| Molecular Weight | 188.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroquinoline Standards
- 2-Chloroquinoline-5-carbonitrile (CAS 1231761-06-0)
- 2-Chloroquinoline-8-carbonitrile (CAS 1231761-07-1)
- 8-Chloroquinoline-2-carbonitrile (CAS 1231761-08-2)
- 5-Chloroquinoline-4-carbonitrile (CAS 1231761-11-7)
- 8-Chloroquinoline-5-carbonitrile (CAS 1256463-59-8)
- 4-Chloroquinoline-8-carbonitrile (CAS 132664-45-0)
- 7-Chloroquinoline-4-carbonitrile (CAS 13337-75-2)
- 2-Chloroquinoline-7-carbonitrile (CAS 1352443-52-7)
Recommended Standards
- 8-Chloroisoquinoline-5-carbonitrile (CAS 1256463-61-2)
- 3-Chloroisoquinoline-4-carbonitrile (CAS 1256463-73-6)
- 5-Chloroisoquinoline-8-carbonitrile (CAS 1256463-60-1)
- 1-Chloroisoquinoline-6-carbonitrile (CAS 1260664-41-2)
- 3-Amino-N-(tert-butyl)propanamide (CAS 209467-48-1)
- 4-Methyl-2-((piperidin-3-ylmethyl)thio)pyrimidine hydrochloride (CAS 1420873-93-3)
- 1-(Difluoromethyl)-2-fluoro-3-iodobenzene (CAS 1261479-13-3)
- 5-(tert-Butyl)benzoxazole-2-methanamine (CAS 1119449-45-4)
- 2,2-Dibromo-4,4,4-trifluorobutanoic acid (CAS 1210691-01-2)
- Phenol, 2-(1,1-dimethylethyl)-6-methyl-4-[3-[[2,4,8,10-tetrakis(1,1-dimethylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-yl]oxy]propyl]- (CAS 203255-81-6)
- Methyl 2-(difluoromethoxy)-5-methylbenzoate (CAS 639826-20-3)
- 4-Chloro-2-((2,6-diethylphenyl)amino)thiazole-5-carbaldehyde (CAS 756859-03-7)
- 2-(3,4-Dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one (CAS 6068-80-0)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com