2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol CAS 1256781-61-9
| CAS No. | 1256781-61-9 |
| Molecular Formula | C12H15BBr2O3 |
| Molecular Weight | 377.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1256781-61-9), molecular formula C12H15BBr2O3 and molecular weight 377.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (C12H15BBr2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BBr2O3 |
| Molecular Weight | 377.86 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
Related Dibromo Standards
- 2,5-Dibromo-3-iodopyridin-4-amine (CAS 1227268-81-6)
- 2,6-Dibromo-4-iodophenol (CAS 187407-15-4)
- 2,4-Dibromo-6-iodophenol (CAS 53872-06-3)
- 3,5-Dibromo-4-iodophenol (CAS 556038-75-6)
- Methyl 3,5-dibromo-4-(trifluoromethoxy)benzoate (CAS 1350760-69-8)
- 2,3-Dibromo-7,8-Difluorodibenzo-p-Dioxin (CAS 50585-43-8)
- Ethyl 4,6-dibromo-5-hydroxy-2-methyl-1-benzofuran-3-carboxylate (CAS 7287-42-5)
- 5-(3,5-Dibromo-4-hydroxy-benzylidene)-2-thioxo-imidazolidin-4-one (CAS 127378-87-4)
Recommended Standards
- 2-(1-(2-Chloro-6-fluorobenzyl)piperidin-4-yl)-5-(furan-2-yl)-1,3,4-thiadiazole (CAS 1226431-16-8)
- (E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide (CAS 477888-28-1)
- Holmium(III) oxide (CAS 12055-62-8)
- 3-(3-Chloro-4-methoxyphenyl)-N-(9H-fluoren-2-yl)propanamide (CAS 853315-02-3)
- Ethyl 5-cyano-2-oxovalerate (CAS 857431-56-2)
- 1-(difluoromethylsulfonyl)piperidin-4-ol (CAS 1156133-61-7)
- Racemic-(3S,3aS,6aR)-tert-butyl 3-hydroxyhexahydro-1H-furo[3,4-b]pyrrole-1-carboxylate (CAS 1251014-36-4)
- Oclacitinib impurity 10 (CAS CATO-C4X-301810)
- N-Methyl-2-(1H-pyrazol-3-yl)-1H-indole-4-carboxamide (CAS 827317-51-1)
- 4-Bromo-N-(2-methylphenyl)benzamide (CAS 106736-05-4)
- (2-Chloropyridin-3-yl)-[4-(hydroxymethyl)piperidin-1-yl]methanone (CAS 1094301-19-5)
- 5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole, 97% (CAS 478828-53-4)
- 2-(4,4-Bis(methoxymethyl)cyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2375650-99-8)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com