(E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide CAS 477888-28-1
| CAS No. | 477888-28-1 |
| Molecular Formula | C23H20ClNO2 |
| Molecular Weight | 377.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 377.86 g/mol gives (E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide (CAS 477888-28-1) is a high-purity analytical reference standard with the molecular formula C23H20ClNO2 and a molecular weight of 377.86 g/mol.
The molecular framework of (E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide (C23H20ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-3-(4-(benzyloxy)phenyl)-N-(4-chlorobenzyl)acrylamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H20ClNO2 |
| Molecular Weight | 377.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 2-(4-(Benzyloxy)-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1218790-07-8)
- 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1257078-54-8)
- 2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 779331-12-3)
- 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 2096995-52-5)
- (R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-bromophenyl)propanoic acid (CAS 123098-44-2)
- 2-(((Benzyloxy)carbonyl)amino)-3-(3-bromophenyl)propanoic acid (CAS 331955-30-7)
- 2-(((Benzyloxy)carbonyl)amino)-3-(4-bromophenyl)propanoic acid (CAS 82611-57-2)
- 3-(((Benzyloxy)carbonyl)amino)-3-(3-bromophenyl)propanoic acid (CAS 778598-15-5)
Recommended Standards
- 2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1256781-61-9)
- 3-(3-Chloro-4-methoxyphenyl)-N-(9H-fluoren-2-yl)propanamide (CAS 853315-02-3)
- 2-(1-(2-Chloro-6-fluorobenzyl)piperidin-4-yl)-5-(furan-2-yl)-1,3,4-thiadiazole (CAS 1226431-16-8)
- 3-Benzhydryl-5-(4-chloro-2-methylphenoxy)-4,5-dihydroisoxazole (CAS 89249-67-2)
- Ethyl 3-[(5-chloro-2-fluorophenyl)amino]-2-cyanoprop-2-enoate (CAS 1181482-69-8)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354486-23-9)
- 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-(4-(trifluoromethyl)benzyl)-1H-pyrazole (CAS 477711-64-1)
- 4-Amino-2-butylisoindoline-1,3-dione (CAS 6305-66-4)
- 4-Bromo-3-(3,4-dimethylphenyl)-3-fluoropropiophenone (CAS 898779-50-5)
- 2-Oxo-2-((1-phenylethyl)amino)ethyl 4-cyanobenzoate (CAS 380484-51-5)
- 3-[(4-Fluorobenzyl)oxy]aniline (CAS 79808-10-9)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
- 1-(3-Chloro-4-propoxyphenyl)propan-1-one (CAS 1159695-98-3)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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